Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia

Aims. To evaluate transcutaneous oximetry as a method for diagnostics and monitoring in patients with diabetes mellitus (DM) and critical limb ischemia (CLI) after percutaneous transluminal balloon angioplasty (PTBA). Materials and Methods. We enrolled 126 patients with DM and CLI for participatio...

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Main Authors: Olga Nikolaevna Bondarenko, N L Ayubova, Gagik Radikovich Galstyan, Ivan Ivanovich Dedov
Format: Article
Language:English
Published: Endocrinology Research Centre 2013-03-01
Series:Сахарный диабет
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Online Access:https://www.dia-endojournals.ru/jour/article/view/3594
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author Olga Nikolaevna Bondarenko
N L Ayubova
Gagik Radikovich Galstyan
Ivan Ivanovich Dedov
author_facet Olga Nikolaevna Bondarenko
N L Ayubova
Gagik Radikovich Galstyan
Ivan Ivanovich Dedov
author_sort Olga Nikolaevna Bondarenko
collection DOAJ
description Aims. To evaluate transcutaneous oximetry as a method for diagnostics and monitoring in patients with diabetes mellitus (DM) and critical limb ischemia (CLI) after percutaneous transluminal balloon angioplasty (PTBA). Materials and Methods. We enrolled 126 patients with DM and CLI for participation in this study (148 limbs in total). 22 patients underwent PTBA on both lower limbs, and 104 ? on single limb. Transcutaneous oximetry and duplex ultrasonography of lower limb arteries was performed prior to PTBA with subsequent examinations on 5-7th days, 1st, 3rd and 6th month after intervention. Transcu- taneous oxygen tension (TcpO2) was measured by Radiometer (Copenhagen) oximeter system. Duplex ultrasonography was performed on Voluson 730? Expert system (GE Medical Systems Kretztechnik GmbH&Co OHG, Austria). Results. Multiple factor analysis suggests that results of TcpO2 monitoring prior to and after PTBA are influenced by presence of ischemic heart disease, severe lower limb infections, serum creatinine, arterial hypertension and lower limb reperfusion edema. We observed a strong correlation of TcpO2 with the degree of anterior tibial artery and dorsal pedis artery occlusion. Conclusion. Transcutaneous oximetry allows evaluation of CLI severity and efficiency of PTBA in the majority oа patients with DM and CLI. Certain comorbidities impose limitations on this technique. Efficiency of endovascular intervention should be evaluated based on complex non-invasive examination, clinical data and signs of CLI.
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spelling doaj-art-5d287fb981ba46cbaaad0e80bfd7b1a42025-08-20T02:29:34ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782013-03-01161334210.14341/2072-0351-35943564Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemiaOlga Nikolaevna Bondarenko0N L Ayubova1Gagik Radikovich Galstyan2Ivan Ivanovich Dedov3Endocrinology Research Centre, MoscowEndocrinology Research Centre, MoscowEndocrinology Research Centre, MoscowEndocrinology Research Centre, MoscowAims. To evaluate transcutaneous oximetry as a method for diagnostics and monitoring in patients with diabetes mellitus (DM) and critical limb ischemia (CLI) after percutaneous transluminal balloon angioplasty (PTBA). Materials and Methods. We enrolled 126 patients with DM and CLI for participation in this study (148 limbs in total). 22 patients underwent PTBA on both lower limbs, and 104 ? on single limb. Transcutaneous oximetry and duplex ultrasonography of lower limb arteries was performed prior to PTBA with subsequent examinations on 5-7th days, 1st, 3rd and 6th month after intervention. Transcu- taneous oxygen tension (TcpO2) was measured by Radiometer (Copenhagen) oximeter system. Duplex ultrasonography was performed on Voluson 730? Expert system (GE Medical Systems Kretztechnik GmbH&Co OHG, Austria). Results. Multiple factor analysis suggests that results of TcpO2 monitoring prior to and after PTBA are influenced by presence of ischemic heart disease, severe lower limb infections, serum creatinine, arterial hypertension and lower limb reperfusion edema. We observed a strong correlation of TcpO2 with the degree of anterior tibial artery and dorsal pedis artery occlusion. Conclusion. Transcutaneous oximetry allows evaluation of CLI severity and efficiency of PTBA in the majority oа patients with DM and CLI. Certain comorbidities impose limitations on this technique. Efficiency of endovascular intervention should be evaluated based on complex non-invasive examination, clinical data and signs of CLI.https://www.dia-endojournals.ru/jour/article/view/3594transcutaneous oximetrycritical limb ischemiapercutaneous transluminal balloon angioplastydiabetes mellitus
spellingShingle Olga Nikolaevna Bondarenko
N L Ayubova
Gagik Radikovich Galstyan
Ivan Ivanovich Dedov
Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
Сахарный диабет
transcutaneous oximetry
critical limb ischemia
percutaneous transluminal balloon angioplasty
diabetes mellitus
title Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_full Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_fullStr Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_full_unstemmed Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_short Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_sort transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
topic transcutaneous oximetry
critical limb ischemia
percutaneous transluminal balloon angioplasty
diabetes mellitus
url https://www.dia-endojournals.ru/jour/article/view/3594
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AT nlayubova transcutaneousoximetrymonitoringinpatientswithtype2diabetesmellitusandcriticallimbischemia
AT gagikradikovichgalstyan transcutaneousoximetrymonitoringinpatientswithtype2diabetesmellitusandcriticallimbischemia
AT ivanivanovichdedov transcutaneousoximetrymonitoringinpatientswithtype2diabetesmellitusandcriticallimbischemia