Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of Iran
Toxoplasma gondii is an obligate intracellular protozoan parasite causing toxoplasmosis in animals and humans. Primary maternal infection with toxoplasmosis during pregnancy is frequently associated with transplacental transmission to the fetus. However it is not certain whether Toxoplasma infecti...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2015/764369 |
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| author | J. Saki N. Mohammadpour F. Moramezi S. Khademvatan |
| author_facet | J. Saki N. Mohammadpour F. Moramezi S. Khademvatan |
| author_sort | J. Saki |
| collection | DOAJ |
| description | Toxoplasma gondii is an obligate intracellular protozoan parasite causing toxoplasmosis in animals and humans. Primary maternal infection with toxoplasmosis during pregnancy is frequently associated with transplacental transmission to the fetus. However it is not certain whether Toxoplasma infection can cause recurrent abortion. The aim of this study was to determine the relationship between Toxoplasma infection and abortion via detection of anti-Toxoplasma gondii antibodies in sera of women with obstetrical problems and compare the results with control group consisting of women with history of normal delivery. Sera from 130 women with abortion and sera of 130 women with normal delivery were tested for IgG and IgM anti-Toxoplasma gondii antibodies by ELISA method. The present study revealed 24.6% of the samples with abortion and 21.5% of the samples with normal delivery were positive for IgG antibodies. However, statistical analysis indicated no significant differences (P>0.05). In addition, IgM antibody was detected in one woman who had aborted but not in women with normal childbirth. This study showed no significant difference between the case and control groups in IgG anti-Toxoplasma antibody but detected one sample with IgM antibodies in woman with abortion during the first trimester of pregnancy. In order to determine the relationship between Toxoplasma infection and abortion, anti-Toxoplasma IgG avidity and PCR to discriminate between recent and prior infections are recommended. |
| format | Article |
| id | doaj-art-5d27eb191eac4e609028997e8643001b |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-5d27eb191eac4e609028997e8643001b2025-02-03T01:24:04ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/764369764369Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of IranJ. Saki0N. Mohammadpour1F. Moramezi2S. Khademvatan3Department of Medical Parasitology and Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranDepartment of Medical Parasitology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranDepartment of Gynecology, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranDepartment of Medical Parasitology and Mycology & Social Determinants of Health Research Center, Urmia University of Medical Sciences, Urmia, IranToxoplasma gondii is an obligate intracellular protozoan parasite causing toxoplasmosis in animals and humans. Primary maternal infection with toxoplasmosis during pregnancy is frequently associated with transplacental transmission to the fetus. However it is not certain whether Toxoplasma infection can cause recurrent abortion. The aim of this study was to determine the relationship between Toxoplasma infection and abortion via detection of anti-Toxoplasma gondii antibodies in sera of women with obstetrical problems and compare the results with control group consisting of women with history of normal delivery. Sera from 130 women with abortion and sera of 130 women with normal delivery were tested for IgG and IgM anti-Toxoplasma gondii antibodies by ELISA method. The present study revealed 24.6% of the samples with abortion and 21.5% of the samples with normal delivery were positive for IgG antibodies. However, statistical analysis indicated no significant differences (P>0.05). In addition, IgM antibody was detected in one woman who had aborted but not in women with normal childbirth. This study showed no significant difference between the case and control groups in IgG anti-Toxoplasma antibody but detected one sample with IgM antibodies in woman with abortion during the first trimester of pregnancy. In order to determine the relationship between Toxoplasma infection and abortion, anti-Toxoplasma IgG avidity and PCR to discriminate between recent and prior infections are recommended.http://dx.doi.org/10.1155/2015/764369 |
| spellingShingle | J. Saki N. Mohammadpour F. Moramezi S. Khademvatan Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of Iran The Scientific World Journal |
| title | Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of Iran |
| title_full | Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of Iran |
| title_fullStr | Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of Iran |
| title_full_unstemmed | Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of Iran |
| title_short | Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of Iran |
| title_sort | seroprevalence of toxoplasma gondii in women who have aborted in comparison with the women with normal delivery in ahvaz southwest of iran |
| url | http://dx.doi.org/10.1155/2015/764369 |
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