Cellular senescence defining the disease characteristics of Crohn’s disease

Cellular senescence defining the disease characteristics of Crohn’s disease

BackgroundCrohn’s disease (CD) is a complex and heterogeneous inflammatory disease whose most important feature is immune dysregulation. As a basic cell response, cellular senescence (CS) can regulate the immune response involved in a variety of inflammatory diseases. However, the role of CS in the...

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Bibliographic Details
Main Authors: Wenyu Zhang, Xianzong Ma, Wenqing Tian, Yongsheng Teng, Meihua Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
Crohn’s disease
cellular senescence
machine learning
immune infiltration heterogeneity
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1616531/full
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