CPNE5 overexpression inhibits cardiomyocytes apoptosis by promoting the degradation of FAS receptor

CPNE5 overexpression inhibits cardiomyocytes apoptosis by promoting the degradation of FAS receptor

Summary: CPNE5, a member of the Copine family, is characterized by its membrane-binding properties and functions as a regulatory modulator of intracellular signaling through the spatial redistribution of interacting protein partners. Emerging evidence has demonstrated that CPNE3 exerts cardioprotect...

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Main Authors: Tingting Zhao, Yangjinming Bai, Yudong Fei, Zhixing Wei, Pengcheng Yao, Qianji Che, Yichao Zhang, Ji Yan, Kaiyan Chen, Zhengyang Wu, Junhao Qiu, Yuepeng Wang, Wei Li, Qian Wang, Yigang Li
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:iScience
Subjects:
Rodent cardiology
Rodent molecular biology
Biological sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225015639
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http://www.sciencedirect.com/science/article/pii/S2589004225015639

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