Factors associated with HIV viremia in transgender women and transvestites in five Brazilian capitals, 2019-2021: a multicenter study

ABSTRACT Objective To analyze factors associated with detectable HIV viremia among transgender women/transvestites (TWT) in five Brazilian capitals. Methods : This was a cross-sectional study using data from a sample of TWT with HIV-positive serology and detectable viral load (VL), between 2019 an...

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Main Authors: Claudia Renata dos Santos Barros, Elaine Monteiro Matsuda, Aline Borges Moreira da Rocha, Giselle Ibete Silva López-Lopes, Norberto Camilo Campos, Luís Fernando de Macedo Brígido, Katia Cristina Bassichetto, Maria Amelia de Sousa Mascena Veras
Format: Article
Language:English
Published: Ministério da Saúde do Brasil 2024-12-01
Series:Epidemiologia e Serviços de Saúde
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222024001300206&lng=en&tlng=en
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author Claudia Renata dos Santos Barros
Elaine Monteiro Matsuda
Aline Borges Moreira da Rocha
Giselle Ibete Silva López-Lopes
Norberto Camilo Campos
Luís Fernando de Macedo Brígido
Katia Cristina Bassichetto
Maria Amelia de Sousa Mascena Veras
author_facet Claudia Renata dos Santos Barros
Elaine Monteiro Matsuda
Aline Borges Moreira da Rocha
Giselle Ibete Silva López-Lopes
Norberto Camilo Campos
Luís Fernando de Macedo Brígido
Katia Cristina Bassichetto
Maria Amelia de Sousa Mascena Veras
author_sort Claudia Renata dos Santos Barros
collection DOAJ
description ABSTRACT Objective To analyze factors associated with detectable HIV viremia among transgender women/transvestites (TWT) in five Brazilian capitals. Methods : This was a cross-sectional study using data from a sample of TWT with HIV-positive serology and detectable viral load (VL), between 2019 and 2021. The dependent and independent variables were, respectively: viral load measurement, socioeconomic/demographic characteristics; alcohol/drug use; and self-perceived mental health. Poisson regression with robust variance was used. Results : A total of 425 TWT tested positive for HIV and underwent VL measurement, 179 (42.0%) presented detectable viremia. Factors positively associated with detectability were: younger age (PR=2.26; 95%CI 1.13;4.51), poorer housing conditions (PR=2.72; 95%CI 1.30;5.68) and poor/very poor mental health (PR=1.70; 95%CI 1.08;2.66). The use of antiretroviral drugs was a protective factor against detectability (PR=0.29; 95%CI 0.30;0.61). Conclusion The factors associated with unsuppressed viral load highlight vulnerability related to gender identity that have a negative impact, despite the majority of participants being on antiretroviral therapy (ART).
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spelling doaj-art-5d06b8f53e384b4687fe895c75fe5c322025-08-20T02:36:42ZengMinistério da Saúde do BrasilEpidemiologia e Serviços de Saúde2237-96222024-12-0133spe110.1590/s2237-96222024v33e2024412.especial.enFactors associated with HIV viremia in transgender women and transvestites in five Brazilian capitals, 2019-2021: a multicenter studyClaudia Renata dos Santos Barroshttps://orcid.org/0000-0002-1582-2010Elaine Monteiro Matsudahttps://orcid.org/0000-0002-0254-4154Aline Borges Moreira da Rochahttps://orcid.org/0000-0003-0558-6672Giselle Ibete Silva López-Lopeshttps://orcid.org/0000-0002-4564-3208Norberto Camilo Camposhttps://orcid.org/0000-0003-1425-9825Luís Fernando de Macedo Brígidohttps://orcid.org/0000-0002-1022-7837Katia Cristina Bassichettohttps://orcid.org/0000-0003-3645-025XMaria Amelia de Sousa Mascena Verashttps://orcid.org/0000-0002-1159-5762ABSTRACT Objective To analyze factors associated with detectable HIV viremia among transgender women/transvestites (TWT) in five Brazilian capitals. Methods : This was a cross-sectional study using data from a sample of TWT with HIV-positive serology and detectable viral load (VL), between 2019 and 2021. The dependent and independent variables were, respectively: viral load measurement, socioeconomic/demographic characteristics; alcohol/drug use; and self-perceived mental health. Poisson regression with robust variance was used. Results : A total of 425 TWT tested positive for HIV and underwent VL measurement, 179 (42.0%) presented detectable viremia. Factors positively associated with detectability were: younger age (PR=2.26; 95%CI 1.13;4.51), poorer housing conditions (PR=2.72; 95%CI 1.30;5.68) and poor/very poor mental health (PR=1.70; 95%CI 1.08;2.66). The use of antiretroviral drugs was a protective factor against detectability (PR=0.29; 95%CI 0.30;0.61). Conclusion The factors associated with unsuppressed viral load highlight vulnerability related to gender identity that have a negative impact, despite the majority of participants being on antiretroviral therapy (ART).http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222024001300206&lng=en&tlng=enAntiretroviral therapyViral LoadTranssexual WomanTransvestitesCross-Sectional Study
spellingShingle Claudia Renata dos Santos Barros
Elaine Monteiro Matsuda
Aline Borges Moreira da Rocha
Giselle Ibete Silva López-Lopes
Norberto Camilo Campos
Luís Fernando de Macedo Brígido
Katia Cristina Bassichetto
Maria Amelia de Sousa Mascena Veras
Factors associated with HIV viremia in transgender women and transvestites in five Brazilian capitals, 2019-2021: a multicenter study
Epidemiologia e Serviços de Saúde
Antiretroviral therapy
Viral Load
Transsexual Woman
Transvestites
Cross-Sectional Study
title Factors associated with HIV viremia in transgender women and transvestites in five Brazilian capitals, 2019-2021: a multicenter study
title_full Factors associated with HIV viremia in transgender women and transvestites in five Brazilian capitals, 2019-2021: a multicenter study
title_fullStr Factors associated with HIV viremia in transgender women and transvestites in five Brazilian capitals, 2019-2021: a multicenter study
title_full_unstemmed Factors associated with HIV viremia in transgender women and transvestites in five Brazilian capitals, 2019-2021: a multicenter study
title_short Factors associated with HIV viremia in transgender women and transvestites in five Brazilian capitals, 2019-2021: a multicenter study
title_sort factors associated with hiv viremia in transgender women and transvestites in five brazilian capitals 2019 2021 a multicenter study
topic Antiretroviral therapy
Viral Load
Transsexual Woman
Transvestites
Cross-Sectional Study
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222024001300206&lng=en&tlng=en
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