Endangered Lymphocytes: The Effects of Alloxan and Streptozotocin on Immune Cells in Type 1 Induced Diabetes

Alloxan (ALX) and streptozotocin (STZ) are extensively used to induce type 1 diabetes (T1D) in animal models. This study is aimed at evaluating the differences in immune parameters caused by ALX and STZ. T1D was induced either with ALX or with STZ, and the animals were followed for up to 180 days. B...

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Main Authors: Luiz A. D. Queiroz, Josiane B. Assis, João P. T. Guimarães, Emanuella S. A. Sousa, Anália C. Milhomem, Karen K. S. Sunahara, Anderson Sá-Nunes, Joilson O. Martins
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2021/9940009
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