Multi-omics analysis of copper metabolism-related molecular subtypes and risk stratification for osteosarcoma

Multi-omics analysis of copper metabolism-related molecular subtypes and risk stratification for osteosarcoma

Abstract Background As the most common primary malignant bone tumor, further investigation into risk stratification for osteosarcoma (OS) prognosis is of significant clinical importance. Copper is essential for bone metabolism; however, its specific role in OS remains unclear. Methods The expression...

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Bibliographic Details
Main Authors: Yang Zhang, Wen Liu, Dayong Liu, Xiaopeng Li, Qingshan Zhuang, Quan Sun, Xiaolin Wu, Feng Li
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
Subjects:
Osteosarcoma
Copper metabolism
Immune microenvironment
Single-cell sequencing
APOA4
Online Access:https://doi.org/10.1007/s12672-025-02273-0
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