Alveolar bone loss induced by high alcohol consumption in rats
Objective: The aim of the present study was to assess the effect of regular and constant long-term alcohol consumption on the percentage of the remaining periodontal bone support (PBS) and periodontal bone loss (PBL) in adult rats. Material and Methods: Fifty-four (54) rats were divided into 3 grou...
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| Format: | Article |
| Language: | English |
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Universidade Estadual Paulista
2017-12-01
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| Series: | Brazilian Dental Science |
| Online Access: | https://ojs.ict.unesp.br/index.php/cob/article/view/1456 |
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| author | Daniela Martins de Souza Alan de Aquino Silva Kauê Alberto Pereira Vitor Sulz Gonsalves Vinicius Anéas Rodrigues Claudemir de Carvalho de Carvalho |
| author_facet | Daniela Martins de Souza Alan de Aquino Silva Kauê Alberto Pereira Vitor Sulz Gonsalves Vinicius Anéas Rodrigues Claudemir de Carvalho de Carvalho |
| author_sort | Daniela Martins de Souza |
| collection | DOAJ |
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Objective: The aim of the present study was to assess the effect of regular and constant long-term alcohol consumption on the percentage of the remaining periodontal bone support (PBS) and periodontal bone loss (PBL) in adult rats. Material and Methods: Fifty-four (54) rats were divided into 3 groups: Control (daily water intake, n=18) daily alcohol intake (20% ethanol, n=18) and social alcohol intake (20% ethanol 2x a week, n=18). The rats were treated with continuous free-choice access to both ethanol consumption frequencies. They were euthanized after 90 days and their left mandibles were radiographed for PBS measuring. The same left mandibles were defleshed and stained. The PBL was morphometrically assessed by measuring the distance between cement-enamel junction and alveolar bone crest. Results: Did not show difference (p > 0.05) in the amount of consumed alcohol between the social and daily intake groups. Rats also evidenced lower PBS percentage and higher PBL (p<0.05) in both alcohol consumption groups in comparison to the control. Conclusion: The long-term constant and regular same amount alcohol consumption may cause alveolar bone loss and reduce the remaining periodontal bone support in adult rats. Thus, the alveolar bone loss was associated with the amount of consumed alcohol, rather than with periodicity in periodontitis-free rats.
Keywords
Alveolar Bone Loss; Alcoholism; Ethanol; Periodontal Disease; X-ray.
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| format | Article |
| id | doaj-art-5cfdb806b5084bdda899faa5dcc52e8a |
| institution | Kabale University |
| issn | 2178-6011 |
| language | English |
| publishDate | 2017-12-01 |
| publisher | Universidade Estadual Paulista |
| record_format | Article |
| series | Brazilian Dental Science |
| spelling | doaj-art-5cfdb806b5084bdda899faa5dcc52e8a2025-08-22T19:03:22ZengUniversidade Estadual PaulistaBrazilian Dental Science2178-60112017-12-0120410.14295/bds.2017.v20i4.1456Alveolar bone loss induced by high alcohol consumption in ratsDaniela Martins de Souza0Alan de Aquino Silva1Kauê Alberto Pereira2Vitor Sulz Gonsalves3Vinicius Anéas Rodrigues4Claudemir de Carvalho de Carvalho5Faculty of Pindamonhangaba – Fundação Universitária Vida Cristã – FUNVIC – Pindamonhangaba – SP – Brazil.Faculty of Pindamonhangaba – Fundação Universitária Vida Cristã – FUNVIC – Pindamonhangaba – SP – Brazil.Faculty of Pindamonhangaba – Fundação Universitária Vida Cristã – FUNVIC – Pindamonhangaba – SP – Brazil.Faculty of Pindamonhangaba – Fundação Universitária Vida Cristã – FUNVIC – Pindamonhangaba – SP – Brazil.São Paulo State University (Unesp) – Institute of Science and Technology – São José dos Campos – SP - Brazil.Faculty of Pindamonhangaba – Fundação Universitária Vida Cristã – FUNVIC – Pindamonhangaba – SP – Brazil. Objective: The aim of the present study was to assess the effect of regular and constant long-term alcohol consumption on the percentage of the remaining periodontal bone support (PBS) and periodontal bone loss (PBL) in adult rats. Material and Methods: Fifty-four (54) rats were divided into 3 groups: Control (daily water intake, n=18) daily alcohol intake (20% ethanol, n=18) and social alcohol intake (20% ethanol 2x a week, n=18). The rats were treated with continuous free-choice access to both ethanol consumption frequencies. They were euthanized after 90 days and their left mandibles were radiographed for PBS measuring. The same left mandibles were defleshed and stained. The PBL was morphometrically assessed by measuring the distance between cement-enamel junction and alveolar bone crest. Results: Did not show difference (p > 0.05) in the amount of consumed alcohol between the social and daily intake groups. Rats also evidenced lower PBS percentage and higher PBL (p<0.05) in both alcohol consumption groups in comparison to the control. Conclusion: The long-term constant and regular same amount alcohol consumption may cause alveolar bone loss and reduce the remaining periodontal bone support in adult rats. Thus, the alveolar bone loss was associated with the amount of consumed alcohol, rather than with periodicity in periodontitis-free rats. Keywords Alveolar Bone Loss; Alcoholism; Ethanol; Periodontal Disease; X-ray. https://ojs.ict.unesp.br/index.php/cob/article/view/1456 |
| spellingShingle | Daniela Martins de Souza Alan de Aquino Silva Kauê Alberto Pereira Vitor Sulz Gonsalves Vinicius Anéas Rodrigues Claudemir de Carvalho de Carvalho Alveolar bone loss induced by high alcohol consumption in rats Brazilian Dental Science |
| title | Alveolar bone loss induced by high alcohol consumption in rats |
| title_full | Alveolar bone loss induced by high alcohol consumption in rats |
| title_fullStr | Alveolar bone loss induced by high alcohol consumption in rats |
| title_full_unstemmed | Alveolar bone loss induced by high alcohol consumption in rats |
| title_short | Alveolar bone loss induced by high alcohol consumption in rats |
| title_sort | alveolar bone loss induced by high alcohol consumption in rats |
| url | https://ojs.ict.unesp.br/index.php/cob/article/view/1456 |
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