Biological prostheses use for abdominal wall repair in open abdomen and incisional hernias: a single center results
Introduction: Biological prostheses (BPs) are a feasible option in abdominal wall reconstruction after open abdomen (OA) when primary fascial closure is not achievable or in treating abdominal wall hernias, especially in the presence of a potential or certain contaminated field. The prese...
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Academia.edu Journals
2025-01-01
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| Online Access: | https://www.academia.edu/126747795/Biological_prostheses_use_for_abdominal_wall_repair_in_open_abdomen_and_incisional_hernias_a_single_center_results |
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| author | Daniele Perrina Carlo Vallicelli Federico Coccolini Massimo Sartelli Belinda De Simone Vanni Agnoletti Luca Ansaloni Fausto Catena |
| author_facet | Daniele Perrina Carlo Vallicelli Federico Coccolini Massimo Sartelli Belinda De Simone Vanni Agnoletti Luca Ansaloni Fausto Catena |
| author_sort | Daniele Perrina |
| collection | DOAJ |
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Introduction: Biological prostheses (BPs) are a feasible option in abdominal wall reconstruction after open abdomen (OA) when primary fascial closure is not achievable or in treating abdominal wall hernias, especially in the presence of a potential or certain contaminated field. The present study reports the results of using a porcine dermal matrix for treating OA defects and incisional hernias, as extracted from the International Register of Biological Prostheses. Methods: Twenty-six consecutive patients treated in an emergency setting between July 2018 and March 2023 were analyzed. An acellular porcine dermal matrix was used. The mean follow-up period was 9 months. Statistical analysis was conducted using R (R Core Team, 2020). Results: At 1 year, 1 (3.8%) recurrence was reported, while no recurrence was observed at 1 month. Four patients (15.4%) developed an enterocutaneous fistula, and five patients (19.2%) experienced wound dehiscence. Subcutaneous drain placement was associated with a lower incidence of wound dehiscence (P = 0.042). The overall complication rate (including medical and surgical complications) was 61% at 1 month and 26.3% at 1 year. Conclusions: BPs are a feasible and effective option for reconstructing the abdominal wall after OA or incisional hernia in potentially or confirmed contaminated fields. Subcutaneous drain placement may help prevent wound dehiscence. |
| format | Article |
| id | doaj-art-5cf9e02821554073b8bd7cfc072e3457 |
| institution | DOAJ |
| issn | 2994-435X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Academia.edu Journals |
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| series | Academia Medicine |
| spelling | doaj-art-5cf9e02821554073b8bd7cfc072e34572025-08-20T03:06:20ZengAcademia.edu JournalsAcademia Medicine2994-435X2025-01-012110.20935/AcadMed7455Biological prostheses use for abdominal wall repair in open abdomen and incisional hernias: a single center resultsDaniele Perrina0Carlo Vallicelli1Federico Coccolini2Massimo Sartelli3Belinda De Simone4Vanni Agnoletti5Luca Ansaloni6Fausto Catena7Department of General, Emergency, and Trauma Surgery, Bufalini Hospital, Cesena 47521, Italy.Department of General, Emergency, and Trauma Surgery, Bufalini Hospital, Cesena 47521, Italy.Department of General, Emergency, and Trauma Surgery, University Hospital of Pisa, Pisa 56121, Italy.Department of Surgery, Macerata Hospital, Macerata 62100, Italy.Department of General, Emergency Surgery, Infermi Hospital, Rimini 47921, Italy.Departmento of Anesthesia and Intensive Care Unit, Bufalini Hospital, Cesena 47521, Italy.Department of General, Emergency, and Trauma Surgery, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia 27100, Italy.Department of General, Emergency, and Trauma Surgery, Bufalini Hospital, Cesena 47521, Italy. Introduction: Biological prostheses (BPs) are a feasible option in abdominal wall reconstruction after open abdomen (OA) when primary fascial closure is not achievable or in treating abdominal wall hernias, especially in the presence of a potential or certain contaminated field. The present study reports the results of using a porcine dermal matrix for treating OA defects and incisional hernias, as extracted from the International Register of Biological Prostheses. Methods: Twenty-six consecutive patients treated in an emergency setting between July 2018 and March 2023 were analyzed. An acellular porcine dermal matrix was used. The mean follow-up period was 9 months. Statistical analysis was conducted using R (R Core Team, 2020). Results: At 1 year, 1 (3.8%) recurrence was reported, while no recurrence was observed at 1 month. Four patients (15.4%) developed an enterocutaneous fistula, and five patients (19.2%) experienced wound dehiscence. Subcutaneous drain placement was associated with a lower incidence of wound dehiscence (P = 0.042). The overall complication rate (including medical and surgical complications) was 61% at 1 month and 26.3% at 1 year. Conclusions: BPs are a feasible and effective option for reconstructing the abdominal wall after OA or incisional hernia in potentially or confirmed contaminated fields. Subcutaneous drain placement may help prevent wound dehiscence.https://www.academia.edu/126747795/Biological_prostheses_use_for_abdominal_wall_repair_in_open_abdomen_and_incisional_hernias_a_single_center_results |
| spellingShingle | Daniele Perrina Carlo Vallicelli Federico Coccolini Massimo Sartelli Belinda De Simone Vanni Agnoletti Luca Ansaloni Fausto Catena Biological prostheses use for abdominal wall repair in open abdomen and incisional hernias: a single center results Academia Medicine |
| title | Biological prostheses use for abdominal wall repair in open abdomen and incisional hernias: a single center results |
| title_full | Biological prostheses use for abdominal wall repair in open abdomen and incisional hernias: a single center results |
| title_fullStr | Biological prostheses use for abdominal wall repair in open abdomen and incisional hernias: a single center results |
| title_full_unstemmed | Biological prostheses use for abdominal wall repair in open abdomen and incisional hernias: a single center results |
| title_short | Biological prostheses use for abdominal wall repair in open abdomen and incisional hernias: a single center results |
| title_sort | biological prostheses use for abdominal wall repair in open abdomen and incisional hernias a single center results |
| url | https://www.academia.edu/126747795/Biological_prostheses_use_for_abdominal_wall_repair_in_open_abdomen_and_incisional_hernias_a_single_center_results |
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