Multiparticulate Drug Delivery of Losartan Potassium via Extrusion-Spheronization: Formulation and Dissolution Comparisons
Background: Losartan potassium, an antihypertensive medication, has high solubility and a short half-life that result in potential adverse effects and rapid drug clearance. Multiparticulate drug delivery systems enhance the drug’s bioavailability, decrease patient-to-patient variability, and optimiz...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2024-11-01
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| Series: | BIO Integration |
| Subjects: | |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2024-0079 |
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