AI-based body composition analysis of CT data has the potential to predict disease course in patients with multiple myeloma
Abstract The aim of this study was to evaluate the benefit of a volumetric AI-based body composition analysis (BCA) algorithm in multiple myeloma (MM). Therefore, a retrospective monocentric cohort of 91 MM patients was analyzed. The BCA algorithm, powered by a convolutional neural network, quantifi...
Saved in:
| Main Authors: | Franz Wegner, Malte Maria Sieren, Hanna Grasshoff, Lennart Berkel, Christoph Rowold, Marcel Philipp Röttgerding, Soleiman Khalil, Sam Mogadas, Felix Nensa, René Hosch, Gabriela Riemekasten, Anna Franziska Hamm, Nikolas von Bubnoff, Jörg Barkhausen, Roman Kloeckner, Cyrus Khandanpour, Theo Leitner |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-11560-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Computed tomography-derived quantitative imaging biomarkers enable the prediction of disease manifestations and survival in patients with systemic sclerosis
by: Gabriela Riemekasten, et al.
Published: (2025-06-01) -
Impact of Radiologist Experience on AI Annotation Quality in Chest Radiographs: A Comparative Analysis
by: Malte Michel Multusch, et al.
Published: (2025-03-01) -
Comparison of 6 cycles of isatuximab with lenalidomide, bortezomib and dexamethasone (I-VRd) versus 3 cycles of I-VRd followed by one cycle of high-dose melphalan in newly diagnosed low-risk multiple myeloma. Protocol for a multicenter, prospective, randomized, phase II clinical trial (ELIAS-Trial)
by: Theo Leitner, et al.
Published: (2024-12-01) -
Germline Single-Nucleotide Polymorphism <i>GFI1-36N</i> Causes Alterations in Mitochondrial Metabolism and Leads to Increased ROS-Mediated DNA Damage in a Murine Model of Human Acute Myeloid Leukemia
by: Jan Vorwerk, et al.
Published: (2025-01-01) -
Functional Role of Fatty Acid Synthase for Signal Transduction in Core-Binding Factor Acute Myeloid Leukemia with an Activating c-Kit Mutation
by: Ruimeng Zhuang, et al.
Published: (2025-03-01)