Cryptosporidium in cattle: Assessing the zoonotic risk

Cattle infected with Cryptosporidium can shed large quantities of the environmentally resistant oocysts, which can cause significant diarrhoeal disease, particularly in neonatal calves and in susceptible human populations worldwide. More than ten species of Cryptosporidium have been reported in catt...

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Main Authors: Sugandika Bulumulla, Lihua Xiao, Yaoyu Feng, Amanda Ash, Joshua Aleri, Una Ryan, Amanda D. Barbosa
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Parasitology and Vector-Borne Diseases
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667114X25000391
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author Sugandika Bulumulla
Lihua Xiao
Yaoyu Feng
Amanda Ash
Joshua Aleri
Una Ryan
Amanda D. Barbosa
author_facet Sugandika Bulumulla
Lihua Xiao
Yaoyu Feng
Amanda Ash
Joshua Aleri
Una Ryan
Amanda D. Barbosa
author_sort Sugandika Bulumulla
collection DOAJ
description Cattle infected with Cryptosporidium can shed large quantities of the environmentally resistant oocysts, which can cause significant diarrhoeal disease, particularly in neonatal calves and in susceptible human populations worldwide. More than ten species of Cryptosporidium have been reported in cattle; however, C. parvum dominates in young calves in many countries, with C. ryanae, C. bovis and C. andersoni prevalent in older animals. Cryptosporidium hominis and C. parvum are the main species infecting humans. In most countries, zoonotic cryptosporidiosis is primarily caused by C. parvum IIa subtypes, which also dominates in calves, but in China, C. parvum infections in cattle are exclusively caused by IId subtypes. Outbreak investigations and molecular epidemiological studies support calves as a major source of zoonotic cryptosporidiosis. The zoonotic significance of increasing reports of C. hominis in cattle requires further investigation. Epidemiological investigations designed to better understand the sources and transmission dynamics using improved typing tools are required before better control strategies can be implemented.
format Article
id doaj-art-5cec53df093c406bb9953e7c8f2de2c5
institution Kabale University
issn 2667-114X
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Current Research in Parasitology and Vector-Borne Diseases
spelling doaj-art-5cec53df093c406bb9953e7c8f2de2c52025-08-20T03:27:02ZengElsevierCurrent Research in Parasitology and Vector-Borne Diseases2667-114X2025-01-01810027910.1016/j.crpvbd.2025.100279Cryptosporidium in cattle: Assessing the zoonotic riskSugandika Bulumulla0Lihua Xiao1Yaoyu Feng2Amanda Ash3Joshua Aleri4Una Ryan5Amanda D. Barbosa6Harry Butler Institute, College of Environmental and Life Sciences, Murdoch University, Murdoch, Western Australia, 6150, Australia; Corresponding author.Guangdong Laboratory for Lingnan Modern Agriculture, Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, Center for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, ChinaHarry Butler Institute, College of Environmental and Life Sciences, Murdoch University, Murdoch, Western Australia, 6150, AustraliaVeterinary Consultancy, Perth, Western Australia, AustraliaHarry Butler Institute, College of Environmental and Life Sciences, Murdoch University, Murdoch, Western Australia, 6150, AustraliaHarry Butler Institute, College of Environmental and Life Sciences, Murdoch University, Murdoch, Western Australia, 6150, Australia; CAPES Foundation, Ministry of Education of Brazil, Brasilia, DF, 70040-020, BrazilCattle infected with Cryptosporidium can shed large quantities of the environmentally resistant oocysts, which can cause significant diarrhoeal disease, particularly in neonatal calves and in susceptible human populations worldwide. More than ten species of Cryptosporidium have been reported in cattle; however, C. parvum dominates in young calves in many countries, with C. ryanae, C. bovis and C. andersoni prevalent in older animals. Cryptosporidium hominis and C. parvum are the main species infecting humans. In most countries, zoonotic cryptosporidiosis is primarily caused by C. parvum IIa subtypes, which also dominates in calves, but in China, C. parvum infections in cattle are exclusively caused by IId subtypes. Outbreak investigations and molecular epidemiological studies support calves as a major source of zoonotic cryptosporidiosis. The zoonotic significance of increasing reports of C. hominis in cattle requires further investigation. Epidemiological investigations designed to better understand the sources and transmission dynamics using improved typing tools are required before better control strategies can be implemented.http://www.sciencedirect.com/science/article/pii/S2667114X25000391CryptosporidiumCattleZoonotic transmissionTypingPublic health
spellingShingle Sugandika Bulumulla
Lihua Xiao
Yaoyu Feng
Amanda Ash
Joshua Aleri
Una Ryan
Amanda D. Barbosa
Cryptosporidium in cattle: Assessing the zoonotic risk
Current Research in Parasitology and Vector-Borne Diseases
Cryptosporidium
Cattle
Zoonotic transmission
Typing
Public health
title Cryptosporidium in cattle: Assessing the zoonotic risk
title_full Cryptosporidium in cattle: Assessing the zoonotic risk
title_fullStr Cryptosporidium in cattle: Assessing the zoonotic risk
title_full_unstemmed Cryptosporidium in cattle: Assessing the zoonotic risk
title_short Cryptosporidium in cattle: Assessing the zoonotic risk
title_sort cryptosporidium in cattle assessing the zoonotic risk
topic Cryptosporidium
Cattle
Zoonotic transmission
Typing
Public health
url http://www.sciencedirect.com/science/article/pii/S2667114X25000391
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