Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study

Objectives: The aim of present randomized controlled clinical trial was to clinically evaluate hard tissue changes after extraction socket preservation procedures compared to natural spontaneous healing. Material and Methods: Thirty patients were enrolled in the present study and underwent single...

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Main Authors: Renzo Guarnieri, Luigi Stefanelli, Francesca De Angelis, Francesca Mencio, Giorgio Pompa, Stefano Di Carlo
Format: Article
Language:English
Published: Lithuanian University of Health Sciences, Faculty of Odontology 2017-03-01
Series:eJournal of Oral Maxillofacial Research
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Online Access:http://www.ejomr.org/JOMR/archives/2017/3/e5/v8n3e5ht.htm
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author Renzo Guarnieri
Luigi Stefanelli
Francesca De Angelis
Francesca Mencio
Giorgio Pompa
Stefano Di Carlo
author_facet Renzo Guarnieri
Luigi Stefanelli
Francesca De Angelis
Francesca Mencio
Giorgio Pompa
Stefano Di Carlo
author_sort Renzo Guarnieri
collection DOAJ
description Objectives: The aim of present randomized controlled clinical trial was to clinically evaluate hard tissue changes after extraction socket preservation procedures compared to natural spontaneous healing. Material and Methods: Thirty patients were enrolled in the present study and underwent single-tooth extraction in the premolar/molar areas. Ten sites were grafted with porcine-derived bone covered by collagen membrane, 10 covered by porcine-derived collagen membrane alone, and 10 underwent natural spontaneous healing. Vertical and horizontal bone changes after 3-month were evaluated at implant placement. Results: The vertical and horizontal bone changes at the extraction sockets treated with collagen membrane alone (vertical: -0.55 [SD 0.11] mm, and horizontal: -1.21 [SD 0.69] mm) and collagen membrane plus porcine-derived bone (vertical: -0.37 [SD 0.7] mm, and horizontal: -0.91 [SD 0.53] mm) were found significantly lower (P < 0.001), when compared to non-grafted sockets (vertical: -2.09 [SD 0.19] mm, and horizontal: -3.96 [SD 0.87] mm). In type 1 extraction sockets, in premolar sites, and in presence of vestibular bone thicknesses ≥ 1.5 mm, the use of collagen membrane alone revealed similar outcomes to those with additional graft material. Conclusions: At the re-entry surgery, extraction sockets grafted with porcine-derived bone and covered by collagen membrane, and extraction sockets covered by porcine-derived collagen membrane alone, showed significantly lower vertical and horizontal bone changes, compared to extraction sockets sites underwent natural spontaneous healing. However, a complete prevention of remodelling is not achievable, irrespective of the technique used.
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spelling doaj-art-5cd34bf149bc4dddaa4274e305cd35632025-08-20T03:56:18ZengLithuanian University of Health Sciences, Faculty of OdontologyeJournal of Oral Maxillofacial Research2029-283X2017-03-0183e510.5037/jomr.2017.8305Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled StudyRenzo GuarnieriLuigi StefanelliFrancesca De AngelisFrancesca MencioGiorgio PompaStefano Di CarloObjectives: The aim of present randomized controlled clinical trial was to clinically evaluate hard tissue changes after extraction socket preservation procedures compared to natural spontaneous healing. Material and Methods: Thirty patients were enrolled in the present study and underwent single-tooth extraction in the premolar/molar areas. Ten sites were grafted with porcine-derived bone covered by collagen membrane, 10 covered by porcine-derived collagen membrane alone, and 10 underwent natural spontaneous healing. Vertical and horizontal bone changes after 3-month were evaluated at implant placement. Results: The vertical and horizontal bone changes at the extraction sockets treated with collagen membrane alone (vertical: -0.55 [SD 0.11] mm, and horizontal: -1.21 [SD 0.69] mm) and collagen membrane plus porcine-derived bone (vertical: -0.37 [SD 0.7] mm, and horizontal: -0.91 [SD 0.53] mm) were found significantly lower (P < 0.001), when compared to non-grafted sockets (vertical: -2.09 [SD 0.19] mm, and horizontal: -3.96 [SD 0.87] mm). In type 1 extraction sockets, in premolar sites, and in presence of vestibular bone thicknesses ≥ 1.5 mm, the use of collagen membrane alone revealed similar outcomes to those with additional graft material. Conclusions: At the re-entry surgery, extraction sockets grafted with porcine-derived bone and covered by collagen membrane, and extraction sockets covered by porcine-derived collagen membrane alone, showed significantly lower vertical and horizontal bone changes, compared to extraction sockets sites underwent natural spontaneous healing. However, a complete prevention of remodelling is not achievable, irrespective of the technique used.http://www.ejomr.org/JOMR/archives/2017/3/e5/v8n3e5ht.htmalveolar bone lossalveolar ridge augmentationbone resorptionbone substitutesdental implantstooth socket
spellingShingle Renzo Guarnieri
Luigi Stefanelli
Francesca De Angelis
Francesca Mencio
Giorgio Pompa
Stefano Di Carlo
Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study
eJournal of Oral Maxillofacial Research
alveolar bone loss
alveolar ridge augmentation
bone resorption
bone substitutes
dental implants
tooth socket
title Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study
title_full Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study
title_fullStr Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study
title_full_unstemmed Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study
title_short Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study
title_sort extraction socket preservation using porcine derived collagen membrane alone or associated with porcine derived bone clinical results of randomized controlled study
topic alveolar bone loss
alveolar ridge augmentation
bone resorption
bone substitutes
dental implants
tooth socket
url http://www.ejomr.org/JOMR/archives/2017/3/e5/v8n3e5ht.htm
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