Novel broad-spectrum activity-based probes to profile malarial cysteine proteases.
Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. In order to study the biological function of these proteases and to chemically...
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| Main Authors: | Michele S Y Tan, Dara Davison, Mateo I Sanchez, Bethany M Anderson, Stephen Howell, Ambrosius Snijders, Laura E Edgington-Mitchell, Edgar Deu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2020-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0227341&type=printable |
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