Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth

ABSTRACT A patient with episodic chest pain, diaphoresis, amaurosis, and dizziness, along with a history of hypertension, presented with electrocardiographic findings of ST elevation in aVR, diffuse T‐wave inversion, and QTc prolongation. Initial diagnosis of NSTEMI was reconsidered after coronary a...

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Main Authors: Jing‐Xiu Li, Xin‐Xin Di, Min Gao, Xue‐Qi Li
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Annals of Noninvasive Electrocardiology
Subjects:
Online Access:https://doi.org/10.1111/anec.70102
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author Jing‐Xiu Li
Xin‐Xin Di
Min Gao
Xue‐Qi Li
author_facet Jing‐Xiu Li
Xin‐Xin Di
Min Gao
Xue‐Qi Li
author_sort Jing‐Xiu Li
collection DOAJ
description ABSTRACT A patient with episodic chest pain, diaphoresis, amaurosis, and dizziness, along with a history of hypertension, presented with electrocardiographic findings of ST elevation in aVR, diffuse T‐wave inversion, and QTc prolongation. Initial diagnosis of NSTEMI was reconsidered after coronary angiography excluded significant stenosis, revealing myocardial bridging. Echocardiography and cardiac MRI showed preserved function without ischemia. Markedly elevated plasma renin and urinary normetanephrine, along with a retroperitoneal mass, suggested paraganglioma. Laparoscopic resection confirmed a 4.0 × 3.5 cm paraganglioma. This case highlights the importance of recognizing atypical ECG patterns that may mimic ischemia in catecholamine‐secreting tumors to guide timely diagnosis and intervention.
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institution Kabale University
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series Annals of Noninvasive Electrocardiology
spelling doaj-art-5cc68963ebd2468e8b8fb094dc8931762025-08-20T03:58:48ZengWileyAnnals of Noninvasive Electrocardiology1082-720X1542-474X2025-07-01304n/an/a10.1111/anec.70102Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying TruthJing‐Xiu Li0Xin‐Xin Di1Min Gao2Xue‐Qi Li3Department of Electrocardiogram The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China Hefei Anhui ChinaDepartment of Electrocardiogram The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China Hefei Anhui ChinaDepartment of Electrocardiogram The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China Hefei Anhui ChinaDepartment of Cardiology The Fourth Affiliated Hospital of Harbin Medical University Harbin ChinaABSTRACT A patient with episodic chest pain, diaphoresis, amaurosis, and dizziness, along with a history of hypertension, presented with electrocardiographic findings of ST elevation in aVR, diffuse T‐wave inversion, and QTc prolongation. Initial diagnosis of NSTEMI was reconsidered after coronary angiography excluded significant stenosis, revealing myocardial bridging. Echocardiography and cardiac MRI showed preserved function without ischemia. Markedly elevated plasma renin and urinary normetanephrine, along with a retroperitoneal mass, suggested paraganglioma. Laparoscopic resection confirmed a 4.0 × 3.5 cm paraganglioma. This case highlights the importance of recognizing atypical ECG patterns that may mimic ischemia in catecholamine‐secreting tumors to guide timely diagnosis and intervention.https://doi.org/10.1111/anec.70102catecholamine‐induced cardiomyopathypheochromocytomawidespread T‐wave inversion
spellingShingle Jing‐Xiu Li
Xin‐Xin Di
Min Gao
Xue‐Qi Li
Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth
Annals of Noninvasive Electrocardiology
catecholamine‐induced cardiomyopathy
pheochromocytoma
widespread T‐wave inversion
title Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth
title_full Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth
title_fullStr Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth
title_full_unstemmed Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth
title_short Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth
title_sort extensive t wave inversion associated with chest pain elucidating the underlying truth
topic catecholamine‐induced cardiomyopathy
pheochromocytoma
widespread T‐wave inversion
url https://doi.org/10.1111/anec.70102
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