Dual-key cooperatively activated DNA regulator for controlling mitochondria-lysosome interactions

Abstract Mitochondria-lysosome interactions are critical for maintaining cellular homeostasis. Although genetically encoded protein based optogenetic technique is developed to regulate such interactions, it still suffers from shortcomings including complicated operation and potential interference to...

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Bibliographic Details
Main Authors: Yang Xiao, Longyi Zhu, Songyuan Du, Xinyi Ge, Lequn Ma, Shengyuan Deng, Kewei Ren
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63040-x
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