Retinal Vascular Tortuosity in a Patient with Weill-Marchesani Syndrome

Weill-Marchesani syndrome (WMS) is a rare connective tissue disorder with characteristic phenotypic skeletal and ocular manifestations. A 28-year-old myopic female presented with an 8-month history of bilateral blurred vision. On examination, she was noted to be of short stature with brachydactyly....

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Main Authors: Kevin Gallagher, Tahrina Salam, Barron Sin, Sandy Gupta, Hadi Zambarakji
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2011/952543
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author Kevin Gallagher
Tahrina Salam
Barron Sin
Sandy Gupta
Hadi Zambarakji
author_facet Kevin Gallagher
Tahrina Salam
Barron Sin
Sandy Gupta
Hadi Zambarakji
author_sort Kevin Gallagher
collection DOAJ
description Weill-Marchesani syndrome (WMS) is a rare connective tissue disorder with characteristic phenotypic skeletal and ocular manifestations. A 28-year-old myopic female presented with an 8-month history of bilateral blurred vision. On examination, she was noted to be of short stature with brachydactyly. On ocular examination, she was found to be spherophakic with bilateral inferiorly subluxated lenses. Serum and urine homocysteine were normal and a syphilis screen was negative. A diagnosis of Weill-Marchesani syndrome was made. Fundoscopy revealed bilateral tortuous retinal vessels. We report the first illustrated case of retinal vascular tortuosity as an ocular manifestation of Weill-Marchesani syndrome.
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-5cbe239b41fd46c8960ed0a711a9656e2025-08-20T02:04:59ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302011-01-01201110.1155/2011/952543952543Retinal Vascular Tortuosity in a Patient with Weill-Marchesani SyndromeKevin Gallagher0Tahrina Salam1Barron Sin2Sandy Gupta3Hadi Zambarakji4Department of Ophthalmology, Whipps Cross University Hospital NHS Trust, Whipps Cross Road, Leytonstone, London E11 1NR, UKDepartment of Ophthalmology, Whipps Cross University Hospital NHS Trust, Whipps Cross Road, Leytonstone, London E11 1NR, UKDepartment of Cardiology, Whipps Cross University Hospital NHS Trust, Whipps Cross Road, Leytonstone, London E11 1NR, UKDepartment of Cardiology, Whipps Cross University Hospital NHS Trust, Whipps Cross Road, Leytonstone, London E11 1NR, UKDepartment of Ophthalmology, Whipps Cross University Hospital NHS Trust, Whipps Cross Road, Leytonstone, London E11 1NR, UKWeill-Marchesani syndrome (WMS) is a rare connective tissue disorder with characteristic phenotypic skeletal and ocular manifestations. A 28-year-old myopic female presented with an 8-month history of bilateral blurred vision. On examination, she was noted to be of short stature with brachydactyly. On ocular examination, she was found to be spherophakic with bilateral inferiorly subluxated lenses. Serum and urine homocysteine were normal and a syphilis screen was negative. A diagnosis of Weill-Marchesani syndrome was made. Fundoscopy revealed bilateral tortuous retinal vessels. We report the first illustrated case of retinal vascular tortuosity as an ocular manifestation of Weill-Marchesani syndrome.http://dx.doi.org/10.1155/2011/952543
spellingShingle Kevin Gallagher
Tahrina Salam
Barron Sin
Sandy Gupta
Hadi Zambarakji
Retinal Vascular Tortuosity in a Patient with Weill-Marchesani Syndrome
Case Reports in Ophthalmological Medicine
title Retinal Vascular Tortuosity in a Patient with Weill-Marchesani Syndrome
title_full Retinal Vascular Tortuosity in a Patient with Weill-Marchesani Syndrome
title_fullStr Retinal Vascular Tortuosity in a Patient with Weill-Marchesani Syndrome
title_full_unstemmed Retinal Vascular Tortuosity in a Patient with Weill-Marchesani Syndrome
title_short Retinal Vascular Tortuosity in a Patient with Weill-Marchesani Syndrome
title_sort retinal vascular tortuosity in a patient with weill marchesani syndrome
url http://dx.doi.org/10.1155/2011/952543
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