Endometriosis and menopause—management strategies based on clinical scenarios

Abstract Endometriosis is largely considered a premenopausal disease with symptoms often improving during menopausal transition. However, 2%–4% of postmenopausal women are affected by endometriosis symptoms. At the same time, many peri‐ and postmenopausal women experience menopausal symptoms and inq...

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Main Authors: Ivika Jakson, Angelica Lindén Hirschberg, Sebastian B. Gidlöf
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Acta Obstetricia et Gynecologica Scandinavica
Subjects:
Online Access:https://doi.org/10.1111/aogs.14583
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author Ivika Jakson
Angelica Lindén Hirschberg
Sebastian B. Gidlöf
author_facet Ivika Jakson
Angelica Lindén Hirschberg
Sebastian B. Gidlöf
author_sort Ivika Jakson
collection DOAJ
description Abstract Endometriosis is largely considered a premenopausal disease with symptoms often improving during menopausal transition. However, 2%–4% of postmenopausal women are affected by endometriosis symptoms. At the same time, many peri‐ and postmenopausal women experience menopausal symptoms and inquire about treatment. Because of the estrogen‐dependent nature of endometriosis, treatment with menopausal hormone therapy requires careful assessment of the patient but should nevertheless be considered. Recurrence of endometriosis symptoms and risk for malignant transformation are potential risks to weigh when prescribing menopausal hormonal therapy. Choice of treatment should be guided by the presence and severity of current endometriosis symptoms, nature of menopausal symptoms, risk assessment of potential contraindications for treatment in patient history, and preferences of the woman after an informative discussion. Recurrence of endometriosis symptoms in a postmenopausal patient should always prompt rigorous evaluation, both in the presence and absence of hormonal treatment. Many recommendations on the topic are based on expert opinion and new studies are urgently needed to obtain evidence for optimal patient care.
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institution Kabale University
issn 0001-6349
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publishDate 2023-10-01
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series Acta Obstetricia et Gynecologica Scandinavica
spelling doaj-art-5cbda270e70347798ba6ae5334de22442025-08-20T03:31:01ZengWileyActa Obstetricia et Gynecologica Scandinavica0001-63491600-04122023-10-01102101323132810.1111/aogs.14583Endometriosis and menopause—management strategies based on clinical scenariosIvika Jakson0Angelica Lindén Hirschberg1Sebastian B. Gidlöf2Department of Gynecology and Reproductive Medicine Karolinska University Hospital Stockholm SwedenDepartment of Gynecology and Reproductive Medicine Karolinska University Hospital Stockholm SwedenDepartment of Gynecology and Reproductive Medicine Karolinska University Hospital Stockholm SwedenAbstract Endometriosis is largely considered a premenopausal disease with symptoms often improving during menopausal transition. However, 2%–4% of postmenopausal women are affected by endometriosis symptoms. At the same time, many peri‐ and postmenopausal women experience menopausal symptoms and inquire about treatment. Because of the estrogen‐dependent nature of endometriosis, treatment with menopausal hormone therapy requires careful assessment of the patient but should nevertheless be considered. Recurrence of endometriosis symptoms and risk for malignant transformation are potential risks to weigh when prescribing menopausal hormonal therapy. Choice of treatment should be guided by the presence and severity of current endometriosis symptoms, nature of menopausal symptoms, risk assessment of potential contraindications for treatment in patient history, and preferences of the woman after an informative discussion. Recurrence of endometriosis symptoms in a postmenopausal patient should always prompt rigorous evaluation, both in the presence and absence of hormonal treatment. Many recommendations on the topic are based on expert opinion and new studies are urgently needed to obtain evidence for optimal patient care.https://doi.org/10.1111/aogs.14583endometriosismenopausal hormone therapymenopausal symptomsmenopauseperimenopause
spellingShingle Ivika Jakson
Angelica Lindén Hirschberg
Sebastian B. Gidlöf
Endometriosis and menopause—management strategies based on clinical scenarios
Acta Obstetricia et Gynecologica Scandinavica
endometriosis
menopausal hormone therapy
menopausal symptoms
menopause
perimenopause
title Endometriosis and menopause—management strategies based on clinical scenarios
title_full Endometriosis and menopause—management strategies based on clinical scenarios
title_fullStr Endometriosis and menopause—management strategies based on clinical scenarios
title_full_unstemmed Endometriosis and menopause—management strategies based on clinical scenarios
title_short Endometriosis and menopause—management strategies based on clinical scenarios
title_sort endometriosis and menopause management strategies based on clinical scenarios
topic endometriosis
menopausal hormone therapy
menopausal symptoms
menopause
perimenopause
url https://doi.org/10.1111/aogs.14583
work_keys_str_mv AT ivikajakson endometriosisandmenopausemanagementstrategiesbasedonclinicalscenarios
AT angelicalindenhirschberg endometriosisandmenopausemanagementstrategiesbasedonclinicalscenarios
AT sebastianbgidlof endometriosisandmenopausemanagementstrategiesbasedonclinicalscenarios