A Randomized Controlled Trial Comparing Suture-Fixation Mucopexy and Doppler-Guided Hemorrhoidal Artery Ligation in Patients with Grade III Hemorrhoids

Background. We aimed to evaluate the effectiveness of a suture-fixation mucopexy procedure by comparing with Doppler-guided hemorrhoidal artery ligation (DGHAL) in the management of patients with grade III hemorrhoids. Methods. This was a randomized controlled trial. One hundred patients with grade...

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Main Authors: Min Zhai, Yong-An Zhang, Zhen-Yi Wang, Jian-Hua Sun, Jie Wen, Qi Zhang, Jin-De Li, Yi-Zheng Wu, Feng Zhou, Hui-Lei Xu
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2016/8143703
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author Min Zhai
Yong-An Zhang
Zhen-Yi Wang
Jian-Hua Sun
Jie Wen
Qi Zhang
Jin-De Li
Yi-Zheng Wu
Feng Zhou
Hui-Lei Xu
author_facet Min Zhai
Yong-An Zhang
Zhen-Yi Wang
Jian-Hua Sun
Jie Wen
Qi Zhang
Jin-De Li
Yi-Zheng Wu
Feng Zhou
Hui-Lei Xu
author_sort Min Zhai
collection DOAJ
description Background. We aimed to evaluate the effectiveness of a suture-fixation mucopexy procedure by comparing with Doppler-guided hemorrhoidal artery ligation (DGHAL) in the management of patients with grade III hemorrhoids. Methods. This was a randomized controlled trial. One hundred patients with grade III hemorrhoids were randomly assigned to receive suture-fixation mucopexy (n=50) or DGHAL (n=50). Outcome assessments were performed at 2 weeks, 12 months, and 24 months. Assessments included resolution of clinical symptoms, postoperative complications, duration of hospitalization, and total costs. Results. At 2 weeks, one (2%) patient in suture-fixation group and four (8%) patients in DGHAL group had persistent prolapsing hemorrhoids. Postoperative bleeding was observed in two patients (4%) in suture-fixation group and one patient in DGHAL group. There was no significant difference in short-term recurrence between groups. Postoperative complications and duration of hospitalization were comparable between the two groups. Rates of recurrence of prolapse or bleeding at 12 months did not differ between groups. However, recurrence of prolapse at 24 months was significantly more common in DGHAL group (19.0% versus 2.3%, p=0.030). Conclusions. Compared with DGHAL, the suture-fixation mucopexy technique had comparable short-term outcomes and favorable long-term outcomes.
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spelling doaj-art-5cbd4a9ba923478996762c99f70785da2025-02-03T00:59:59ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/81437038143703A Randomized Controlled Trial Comparing Suture-Fixation Mucopexy and Doppler-Guided Hemorrhoidal Artery Ligation in Patients with Grade III HemorrhoidsMin Zhai0Yong-An Zhang1Zhen-Yi Wang2Jian-Hua Sun3Jie Wen4Qi Zhang5Jin-De Li6Yi-Zheng Wu7Feng Zhou8Hui-Lei Xu9Department of Anorectal Surgery, The TCM Hospital of Pu Dong New District, Shanghai 201299, ChinaDepartment of Anorectal Surgery, The TCM Hospital of Pu Dong New District, Shanghai 201299, ChinaYueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, ChinaYueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, ChinaDepartment of Anorectal Surgery, The TCM Hospital of Pu Dong New District, Shanghai 201299, ChinaDepartment of Anorectal Surgery, The TCM Hospital of Pu Dong New District, Shanghai 201299, ChinaDepartment of Anorectal Surgery, The TCM Hospital of Pu Dong New District, Shanghai 201299, ChinaDepartment of Anorectal Surgery, The TCM Hospital of Pu Dong New District, Shanghai 201299, ChinaDepartment of Anorectal Surgery, The TCM Hospital of Pu Dong New District, Shanghai 201299, ChinaDepartment of Anorectal Surgery, The TCM Hospital of Pu Dong New District, Shanghai 201299, ChinaBackground. We aimed to evaluate the effectiveness of a suture-fixation mucopexy procedure by comparing with Doppler-guided hemorrhoidal artery ligation (DGHAL) in the management of patients with grade III hemorrhoids. Methods. This was a randomized controlled trial. One hundred patients with grade III hemorrhoids were randomly assigned to receive suture-fixation mucopexy (n=50) or DGHAL (n=50). Outcome assessments were performed at 2 weeks, 12 months, and 24 months. Assessments included resolution of clinical symptoms, postoperative complications, duration of hospitalization, and total costs. Results. At 2 weeks, one (2%) patient in suture-fixation group and four (8%) patients in DGHAL group had persistent prolapsing hemorrhoids. Postoperative bleeding was observed in two patients (4%) in suture-fixation group and one patient in DGHAL group. There was no significant difference in short-term recurrence between groups. Postoperative complications and duration of hospitalization were comparable between the two groups. Rates of recurrence of prolapse or bleeding at 12 months did not differ between groups. However, recurrence of prolapse at 24 months was significantly more common in DGHAL group (19.0% versus 2.3%, p=0.030). Conclusions. Compared with DGHAL, the suture-fixation mucopexy technique had comparable short-term outcomes and favorable long-term outcomes.http://dx.doi.org/10.1155/2016/8143703
spellingShingle Min Zhai
Yong-An Zhang
Zhen-Yi Wang
Jian-Hua Sun
Jie Wen
Qi Zhang
Jin-De Li
Yi-Zheng Wu
Feng Zhou
Hui-Lei Xu
A Randomized Controlled Trial Comparing Suture-Fixation Mucopexy and Doppler-Guided Hemorrhoidal Artery Ligation in Patients with Grade III Hemorrhoids
Gastroenterology Research and Practice
title A Randomized Controlled Trial Comparing Suture-Fixation Mucopexy and Doppler-Guided Hemorrhoidal Artery Ligation in Patients with Grade III Hemorrhoids
title_full A Randomized Controlled Trial Comparing Suture-Fixation Mucopexy and Doppler-Guided Hemorrhoidal Artery Ligation in Patients with Grade III Hemorrhoids
title_fullStr A Randomized Controlled Trial Comparing Suture-Fixation Mucopexy and Doppler-Guided Hemorrhoidal Artery Ligation in Patients with Grade III Hemorrhoids
title_full_unstemmed A Randomized Controlled Trial Comparing Suture-Fixation Mucopexy and Doppler-Guided Hemorrhoidal Artery Ligation in Patients with Grade III Hemorrhoids
title_short A Randomized Controlled Trial Comparing Suture-Fixation Mucopexy and Doppler-Guided Hemorrhoidal Artery Ligation in Patients with Grade III Hemorrhoids
title_sort randomized controlled trial comparing suture fixation mucopexy and doppler guided hemorrhoidal artery ligation in patients with grade iii hemorrhoids
url http://dx.doi.org/10.1155/2016/8143703
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