Increased Na⁺/Ca²⁺ exchanger expression/activity constitutes a point of inflection in the progression to heart failure of hypertensive rats.

Increased Na⁺/Ca²⁺ exchanger expression/activity constitutes a point of inflection in the progression to heart failure of hypertensive rats.

<h4>Unlabelled</h4>Spontaneously hypertensive rat (SHR) constitutes a genetic model widely used to study the natural evolution of hypertensive heart disease. Ca²⁺-handling alterations are known to occur in SHR. However, the putative modifications of Ca²⁺-handling proteins during the prog...

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Main Authors: Jesica S Rodriguez, J Omar Velez Rueda, Margarita Salas, Romina Becerra, Mariano N Di Carlo, Matilde Said, Leticia Vittone, Gustavo Rinaldi, Enrique L Portiansky, Cecilia Mundiña-Weilenmann, Julieta Palomeque, Alicia Mattiazzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096400&type=printable
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