Ancient Schwannoma in Proximity to the Median Nerve in the Midarm of an Elderly Woman
Ancient schwannomas (ASs) are a rare type of schwannomas which arise from the Schwann cells. They are characterized by benign nature and long-standing course. Their histopathological hallmark is hemorrhagic and degenerative changes with nuclear atypia. They can be misdiagnosed as malignant tumors bu...
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Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | Journal of Radiation and Cancer Research |
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| Online Access: | https://journals.lww.com/10.4103/jrcr.jrcr_9_24 |
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| author | Milind A. Deshmukh Vitaladevuni B. Shivkumar Niloy R. Datta |
| author_facet | Milind A. Deshmukh Vitaladevuni B. Shivkumar Niloy R. Datta |
| author_sort | Milind A. Deshmukh |
| collection | DOAJ |
| description | Ancient schwannomas (ASs) are a rare type of schwannomas which arise from the Schwann cells. They are characterized by benign nature and long-standing course. Their histopathological hallmark is hemorrhagic and degenerative changes with nuclear atypia. They can be misdiagnosed as malignant tumors but are differentiated by absence of mitotic activity. The median nerve in the arm is rarely involved. Even rarer is the appearance of ASs away from the main median nerve. We describe a case of AS present in proximity to the median nerve in the midarm of an elderly woman. The tumor grew relatively faster over 1.5 years and the patient presented with pain and swelling in the medial side of the right midarm. Following imaging and histopathological examination (HPE), definitive diagnosis was reached. Surgical excision was done performed and further HPE confirmed AS. The patient was further subjected to external beam radiotherapy (RT; 50 Gy over 5 weeks in 25 fractions) to prevent recurrence. RT was well tolerated, and at 2 months of follow-up, there was absence of any radiological sign of recurrence. The differential diagnoses of AS include sarcomas and tumors of neural origin. History, clinical presentation, imaging, and histopathology findings are critical in arriving at the diagnosis of AS. |
| format | Article |
| id | doaj-art-5cbb76b5d85f4a90ace5e119dc2f31b1 |
| institution | DOAJ |
| issn | 2588-9273 2468-9203 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Radiation and Cancer Research |
| spelling | doaj-art-5cbb76b5d85f4a90ace5e119dc2f31b12025-08-20T02:44:13ZengWolters Kluwer Medknow PublicationsJournal of Radiation and Cancer Research2588-92732468-92032025-04-01162939510.4103/jrcr.jrcr_9_24Ancient Schwannoma in Proximity to the Median Nerve in the Midarm of an Elderly WomanMilind A. DeshmukhVitaladevuni B. ShivkumarNiloy R. DattaAncient schwannomas (ASs) are a rare type of schwannomas which arise from the Schwann cells. They are characterized by benign nature and long-standing course. Their histopathological hallmark is hemorrhagic and degenerative changes with nuclear atypia. They can be misdiagnosed as malignant tumors but are differentiated by absence of mitotic activity. The median nerve in the arm is rarely involved. Even rarer is the appearance of ASs away from the main median nerve. We describe a case of AS present in proximity to the median nerve in the midarm of an elderly woman. The tumor grew relatively faster over 1.5 years and the patient presented with pain and swelling in the medial side of the right midarm. Following imaging and histopathological examination (HPE), definitive diagnosis was reached. Surgical excision was done performed and further HPE confirmed AS. The patient was further subjected to external beam radiotherapy (RT; 50 Gy over 5 weeks in 25 fractions) to prevent recurrence. RT was well tolerated, and at 2 months of follow-up, there was absence of any radiological sign of recurrence. The differential diagnoses of AS include sarcomas and tumors of neural origin. History, clinical presentation, imaging, and histopathology findings are critical in arriving at the diagnosis of AS.https://journals.lww.com/10.4103/jrcr.jrcr_9_24ancient schwannomacase reportmedian nerveschwannoma |
| spellingShingle | Milind A. Deshmukh Vitaladevuni B. Shivkumar Niloy R. Datta Ancient Schwannoma in Proximity to the Median Nerve in the Midarm of an Elderly Woman Journal of Radiation and Cancer Research ancient schwannoma case report median nerve schwannoma |
| title | Ancient Schwannoma in Proximity to the Median Nerve in the Midarm of an Elderly Woman |
| title_full | Ancient Schwannoma in Proximity to the Median Nerve in the Midarm of an Elderly Woman |
| title_fullStr | Ancient Schwannoma in Proximity to the Median Nerve in the Midarm of an Elderly Woman |
| title_full_unstemmed | Ancient Schwannoma in Proximity to the Median Nerve in the Midarm of an Elderly Woman |
| title_short | Ancient Schwannoma in Proximity to the Median Nerve in the Midarm of an Elderly Woman |
| title_sort | ancient schwannoma in proximity to the median nerve in the midarm of an elderly woman |
| topic | ancient schwannoma case report median nerve schwannoma |
| url | https://journals.lww.com/10.4103/jrcr.jrcr_9_24 |
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