Thermosensitive Mucoadhesive Intranasal In Situ Gel of Risperidone for Nose-to-Brain Targeting: Physiochemical and Pharmacokinetics Study

Thermosensitive Mucoadhesive Intranasal In Situ Gel of Risperidone for Nose-to-Brain Targeting: Physiochemical and Pharmacokinetics Study

<b>Background/Objectives:</b> Non-invasive central nervous system (CNS) therapies are limited by complex mechanisms and the blood–brain barrier, but nasal delivery offers a promising alternative. The study planned to develop a non-invasive in situ intranasal mucoadhesive thermosensitive...

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Bibliographic Details
Main Authors: Mahendra Singh, Sanjay Kumar, Ramachandran Vinayagam, Ramachandran Samivel
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceuticals
Subjects:
CNS disorders
diffusion
thermosensitive in situ gels
nose-to-brain targeting
non-invasive
blood–brain barrier
Online Access:https://www.mdpi.com/1424-8247/18/6/871
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