An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception
Abstract Background Adenocarcinoma in an inverted Meckel's diverticulum with intussusception has not been reported to date. We discuss the clinical issues concerning this rare condition and review the relevant literature. Case presentation A 71-year-old Japanese female was referred to our hospi...
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Japan Surgical Society
2023-06-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-023-01680-1 |
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| author | Yamato Miwa Yo Sato Kenichiro Hirano Eiji Sunami Motoko Takahashi Shin-ichi Kosugi Takeshi Suda Go Hasegawa |
| author_facet | Yamato Miwa Yo Sato Kenichiro Hirano Eiji Sunami Motoko Takahashi Shin-ichi Kosugi Takeshi Suda Go Hasegawa |
| author_sort | Yamato Miwa |
| collection | DOAJ |
| description | Abstract Background Adenocarcinoma in an inverted Meckel's diverticulum with intussusception has not been reported to date. We discuss the clinical issues concerning this rare condition and review the relevant literature. Case presentation A 71-year-old Japanese female was referred to our hospital for further investigation of severe anemia. Computed tomography revealed a tumorous lesion in the terminal ileum. Capsule endoscopy did not provide detailed images. Exploratory laparoscopy revealed intussusception in the terminal ileum. An intraluminal tumor 70 cm proximal to the ileocecal valve was observed to be the lead point. Partial resection including the tumor was performed. Macroscopically, a polypoid tumor at the tip of an inverted diverticulum-like structure was observed. The tumor was histologically composed of adenocarcinoma accompanied by gastric and pyloric gland metaplasia in the background mucosa, which was confirmed by immunohistochemical staining. Based on these characteristics, this tumor is considered to have developed from the ectopic gastric mucosa in a Meckel's diverticulum. Conclusions When we encounter patients with unfamiliar lesions in the small bowel, we need to differentiate Meckel's diverticulum related disease. Meckel's diverticulum can invert into the lumen of the small bowel and cause an intussusception, and has potential of malignant transformation. |
| format | Article |
| id | doaj-art-5ca892c1a32e436eab46c04f150eeb64 |
| institution | DOAJ |
| issn | 2198-7793 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-5ca892c1a32e436eab46c04f150eeb642025-08-20T02:53:16ZengJapan Surgical SocietySurgical Case Reports2198-77932023-06-01911610.1186/s40792-023-01680-1An adenocarcinoma in an inverted Meckel’s diverticulum with intussusceptionYamato Miwa0Yo Sato1Kenichiro Hirano2Eiji Sunami3Motoko Takahashi4Shin-ichi Kosugi5Takeshi Suda6Go Hasegawa7Department of Digestive and General Surgery, Uonuma Kikan HospitalDepartment of Digestive and General Surgery, Uonuma Kikan HospitalDepartment of Digestive and General Surgery, Uonuma Kikan HospitalDepartment of Digestive and General Surgery, Uonuma Kikan HospitalDepartment of Digestive and General Surgery, Uonuma Kikan HospitalDepartment of Digestive and General Surgery, Uonuma Kikan HospitalDepartment of Gastroenterology and Hepatology, Uonuma Kikan HospitalDepartment of Pathology, Uonuma Kikan HospitalAbstract Background Adenocarcinoma in an inverted Meckel's diverticulum with intussusception has not been reported to date. We discuss the clinical issues concerning this rare condition and review the relevant literature. Case presentation A 71-year-old Japanese female was referred to our hospital for further investigation of severe anemia. Computed tomography revealed a tumorous lesion in the terminal ileum. Capsule endoscopy did not provide detailed images. Exploratory laparoscopy revealed intussusception in the terminal ileum. An intraluminal tumor 70 cm proximal to the ileocecal valve was observed to be the lead point. Partial resection including the tumor was performed. Macroscopically, a polypoid tumor at the tip of an inverted diverticulum-like structure was observed. The tumor was histologically composed of adenocarcinoma accompanied by gastric and pyloric gland metaplasia in the background mucosa, which was confirmed by immunohistochemical staining. Based on these characteristics, this tumor is considered to have developed from the ectopic gastric mucosa in a Meckel's diverticulum. Conclusions When we encounter patients with unfamiliar lesions in the small bowel, we need to differentiate Meckel's diverticulum related disease. Meckel's diverticulum can invert into the lumen of the small bowel and cause an intussusception, and has potential of malignant transformation.https://doi.org/10.1186/s40792-023-01680-1Inverted Meckel's diverticulumAdenocarcinomaIntussusception |
| spellingShingle | Yamato Miwa Yo Sato Kenichiro Hirano Eiji Sunami Motoko Takahashi Shin-ichi Kosugi Takeshi Suda Go Hasegawa An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception Surgical Case Reports Inverted Meckel's diverticulum Adenocarcinoma Intussusception |
| title | An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception |
| title_full | An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception |
| title_fullStr | An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception |
| title_full_unstemmed | An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception |
| title_short | An adenocarcinoma in an inverted Meckel’s diverticulum with intussusception |
| title_sort | adenocarcinoma in an inverted meckel s diverticulum with intussusception |
| topic | Inverted Meckel's diverticulum Adenocarcinoma Intussusception |
| url | https://doi.org/10.1186/s40792-023-01680-1 |
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