Depression in patients with refractory temporal lobe epilepsy
OBJECTIVE: To evaluate the comorbidity of depressive disorders in patients with refractory temporal lobe epilepsy (TLE). METHOD: We evaluated 25 consecutive patients with refractory TLE (16 women and 9 men), using semi-structured psychiatric interviews, according to the International Classification...
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| Language: | English |
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Thieme Revinter Publicações
2011-10-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000600010&lng=en&tlng=en |
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| author | Eleonora Borges Gonçalves Fernando Cendes |
| author_facet | Eleonora Borges Gonçalves Fernando Cendes |
| author_sort | Eleonora Borges Gonçalves |
| collection | DOAJ |
| description | OBJECTIVE: To evaluate the comorbidity of depressive disorders in patients with refractory temporal lobe epilepsy (TLE). METHOD: We evaluated 25 consecutive patients with refractory TLE (16 women and 9 men), using semi-structured psychiatric interviews, according to the International Classification of Diseases (ICD-10), and the Beck Depression Inventory. RESULTS: Seventeen of 25 patients (68%) had depressive disorder: 6 with dysthymia, three with major depressive episodes and 8 with recurrent depressive disorders. Two (8%) were diagnosed with mixed anxiety and depression. Only 5 of 17 patients (29.4%) were previously diagnosed with depressive disorder and received prior antidepressant treatment. Duration of epilepsy was significantly higher in patients with depressive disorder (p=0.016), but there was no relationship between depression and seizure frequency. CONCLUSION: This study confirmed that depressive disorders are common and underdiagnosed in patients with TLE refractory to AEDs. Patients with longer duration of epilepsy are at higher risk of having depression. |
| format | Article |
| id | doaj-art-5ca5537cfa544890a99b7bbb8abf3c7c |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 2011-10-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-5ca5537cfa544890a99b7bbb8abf3c7c2025-08-20T01:57:08ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272011-10-0169577577710.1590/S0004-282X2011000600010S0004-282X2011000600010Depression in patients with refractory temporal lobe epilepsyEleonora Borges Gonçalves0Fernando Cendes1Universidade Estadual de CampinasUniversidade Estadual de CampinasOBJECTIVE: To evaluate the comorbidity of depressive disorders in patients with refractory temporal lobe epilepsy (TLE). METHOD: We evaluated 25 consecutive patients with refractory TLE (16 women and 9 men), using semi-structured psychiatric interviews, according to the International Classification of Diseases (ICD-10), and the Beck Depression Inventory. RESULTS: Seventeen of 25 patients (68%) had depressive disorder: 6 with dysthymia, three with major depressive episodes and 8 with recurrent depressive disorders. Two (8%) were diagnosed with mixed anxiety and depression. Only 5 of 17 patients (29.4%) were previously diagnosed with depressive disorder and received prior antidepressant treatment. Duration of epilepsy was significantly higher in patients with depressive disorder (p=0.016), but there was no relationship between depression and seizure frequency. CONCLUSION: This study confirmed that depressive disorders are common and underdiagnosed in patients with TLE refractory to AEDs. Patients with longer duration of epilepsy are at higher risk of having depression.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000600010&lng=en&tlng=entranstornos depressivosdepressãoepilepsia do lobo temporal mesialcrises epilépticas |
| spellingShingle | Eleonora Borges Gonçalves Fernando Cendes Depression in patients with refractory temporal lobe epilepsy Arquivos de Neuro-Psiquiatria transtornos depressivos depressão epilepsia do lobo temporal mesial crises epilépticas |
| title | Depression in patients with refractory temporal lobe epilepsy |
| title_full | Depression in patients with refractory temporal lobe epilepsy |
| title_fullStr | Depression in patients with refractory temporal lobe epilepsy |
| title_full_unstemmed | Depression in patients with refractory temporal lobe epilepsy |
| title_short | Depression in patients with refractory temporal lobe epilepsy |
| title_sort | depression in patients with refractory temporal lobe epilepsy |
| topic | transtornos depressivos depressão epilepsia do lobo temporal mesial crises epilépticas |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000600010&lng=en&tlng=en |
| work_keys_str_mv | AT eleonoraborgesgoncalves depressioninpatientswithrefractorytemporallobeepilepsy AT fernandocendes depressioninpatientswithrefractorytemporallobeepilepsy |