Current treatment concepts for osteochondral lesions of the talus

Osteochondral lesions of the talus (OLT) are a well-known cause of ankle joint pain and can sometimes lead to instability. These lesions are not only confined to articular hyaline cartilage, they can also affect the subchondral bone at the weight-bearing aspect of the talar dome. Nonoperative treatm...

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Main Authors: Chen-Chie Wang, Kai-Chiang Yang, Ing-Ho Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Tzu Chi Medical Journal
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Online Access:http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2021;volume=33;issue=3;spage=243;epage=249;aulast=Wang
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author Chen-Chie Wang
Kai-Chiang Yang
Ing-Ho Chen
author_facet Chen-Chie Wang
Kai-Chiang Yang
Ing-Ho Chen
author_sort Chen-Chie Wang
collection DOAJ
description Osteochondral lesions of the talus (OLT) are a well-known cause of ankle joint pain and can sometimes lead to instability. These lesions are not only confined to articular hyaline cartilage, they can also affect the subchondral bone at the weight-bearing aspect of the talar dome. Nonoperative treatment is the preferred option for small lesions, however surgical intervention is recommended for large lesions or those for which conservative treatment has failed. Microfracture, abrasion arthroplasty and multiple drilling are all classified as bone marrow stimulation procedures; they are used to try to recruit precursor cells for cartilage regeneration and are especially suitable for small OLT lesions. For large lesions, osteochondral autografting and allografting are better options to reconstruct the articular defect, as they have better contours and mechanical strength. When there is limited subchondral bone involvement in large lesions, cell-based therapies such as autogenous chondrocyte implantation, potentially combined with a biomaterial matrix, are a promising option and acceptable functional outcomes have been reported. To provide evidence-based recommendations for clinicians, this article evaluates the currently available treatment strategies for OLT and their evolution over the past few decades.
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spelling doaj-art-5ca35b2d4592470782d3d0f91509eeb22025-08-20T02:56:34ZengWolters Kluwer Medknow PublicationsTzu Chi Medical Journal1016-31902223-89562021-01-0133324324910.4103/tcmj.tcmj_106_20Current treatment concepts for osteochondral lesions of the talusChen-Chie WangKai-Chiang YangIng-Ho ChenOsteochondral lesions of the talus (OLT) are a well-known cause of ankle joint pain and can sometimes lead to instability. These lesions are not only confined to articular hyaline cartilage, they can also affect the subchondral bone at the weight-bearing aspect of the talar dome. Nonoperative treatment is the preferred option for small lesions, however surgical intervention is recommended for large lesions or those for which conservative treatment has failed. Microfracture, abrasion arthroplasty and multiple drilling are all classified as bone marrow stimulation procedures; they are used to try to recruit precursor cells for cartilage regeneration and are especially suitable for small OLT lesions. For large lesions, osteochondral autografting and allografting are better options to reconstruct the articular defect, as they have better contours and mechanical strength. When there is limited subchondral bone involvement in large lesions, cell-based therapies such as autogenous chondrocyte implantation, potentially combined with a biomaterial matrix, are a promising option and acceptable functional outcomes have been reported. To provide evidence-based recommendations for clinicians, this article evaluates the currently available treatment strategies for OLT and their evolution over the past few decades.http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2021;volume=33;issue=3;spage=243;epage=249;aulast=Wangmicrofractureosteochondral lesiontalus
spellingShingle Chen-Chie Wang
Kai-Chiang Yang
Ing-Ho Chen
Current treatment concepts for osteochondral lesions of the talus
Tzu Chi Medical Journal
microfracture
osteochondral lesion
talus
title Current treatment concepts for osteochondral lesions of the talus
title_full Current treatment concepts for osteochondral lesions of the talus
title_fullStr Current treatment concepts for osteochondral lesions of the talus
title_full_unstemmed Current treatment concepts for osteochondral lesions of the talus
title_short Current treatment concepts for osteochondral lesions of the talus
title_sort current treatment concepts for osteochondral lesions of the talus
topic microfracture
osteochondral lesion
talus
url http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2021;volume=33;issue=3;spage=243;epage=249;aulast=Wang
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