Melatonin as a potential adjuvant to mitigate depakine‑induced testicular damage in rats through its biological features

Abstract Background Depakine (valproic acid) is an antiepileptic medication that is commonly used as a first-line treatment for a variety of seizures in both adults and children. However, it can result in testicular toxicity by increasing oxidative stress inflammation. Melatonin (MLT) has antioxidan...

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Bibliographic Details
Main Authors: Maggie E. Amer, Mohamed A. Dardoor, Azza I. Othman, Mohamed A. El-Missiry
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Complementary Medicine and Therapies
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Online Access:https://doi.org/10.1186/s12906-025-04969-w
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