Clinical Review of Eosinophilic Esophagitis

Eosinophilic esophagitis is a chronic inflammatory condition characterized by symptoms of esophageal dysfunction and eosinophil infiltration in the esophageal epithelium. The definition of eosinophilic esophagitis continues to evolve, most recently with the characterization of proton pump inhibitor-...

Full description

Saved in:
Bibliographic Details
Main Author: Hyuk Lee
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2018-03-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Subjects:
Online Access:http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.1.3
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850051067718402048
author Hyuk Lee
author_facet Hyuk Lee
author_sort Hyuk Lee
collection DOAJ
description Eosinophilic esophagitis is a chronic inflammatory condition characterized by symptoms of esophageal dysfunction and eosinophil infiltration in the esophageal epithelium. The definition of eosinophilic esophagitis continues to evolve, most recently with the characterization of proton pump inhibitor-responsive esophageal eosinophilia. Diagnosis of eosinophilic esophagitis is based on consensus guidelines, but can be challenging because none of the symptoms, endoscopic findings, or histologic features are specific for eosinophilic esophagitis on their own. For treatment, either oral topical corticosteroids or dietary elimination therapy are reasonable first-line options. The choice will depend on both patient preference and clinician expertise. In cases with severe esophageal strictures, dilation is also performed. Proton pump inhibitors play an important role in current management.
format Article
id doaj-art-5c96b1fbf0284b17baf22df91edc6032
institution DOAJ
issn 1738-3331
language English
publishDate 2018-03-01
publisher Korean College of Helicobacter and Upper Gastrointestinal Research
record_format Article
series The Korean Journal of Helicobacter and Upper Gastrointestinal Research
spelling doaj-art-5c96b1fbf0284b17baf22df91edc60322025-08-20T02:53:16ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312018-03-0118131210.7704/kjhugr.2018.18.1.3kjhugr.2018.18.1.3Clinical Review of Eosinophilic EsophagitisHyuk Lee0Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaEosinophilic esophagitis is a chronic inflammatory condition characterized by symptoms of esophageal dysfunction and eosinophil infiltration in the esophageal epithelium. The definition of eosinophilic esophagitis continues to evolve, most recently with the characterization of proton pump inhibitor-responsive esophageal eosinophilia. Diagnosis of eosinophilic esophagitis is based on consensus guidelines, but can be challenging because none of the symptoms, endoscopic findings, or histologic features are specific for eosinophilic esophagitis on their own. For treatment, either oral topical corticosteroids or dietary elimination therapy are reasonable first-line options. The choice will depend on both patient preference and clinician expertise. In cases with severe esophageal strictures, dilation is also performed. Proton pump inhibitors play an important role in current management.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.1.3DiagnosisEosinophilic esophagitisTherapeutics
spellingShingle Hyuk Lee
Clinical Review of Eosinophilic Esophagitis
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Diagnosis
Eosinophilic esophagitis
Therapeutics
title Clinical Review of Eosinophilic Esophagitis
title_full Clinical Review of Eosinophilic Esophagitis
title_fullStr Clinical Review of Eosinophilic Esophagitis
title_full_unstemmed Clinical Review of Eosinophilic Esophagitis
title_short Clinical Review of Eosinophilic Esophagitis
title_sort clinical review of eosinophilic esophagitis
topic Diagnosis
Eosinophilic esophagitis
Therapeutics
url http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.1.3
work_keys_str_mv AT hyuklee clinicalreviewofeosinophilicesophagitis