Impact of hyperglycaemia on cellular microenvironment and function of endometrium and uterine tube: scoping review focused on infertility in diabetic women

Impact of hyperglycaemia on cellular microenvironment and function of endometrium and uterine tube: scoping review focused on infertility in diabetic women

IntroductionDiabetes mellitus (DM) and associated comorbidities correspond to female infertility by many interrelated mechanisms. Yet most prior research focuses only on ovary dysfunction. Our work evaluates literature mechanisms of DM-induced uterine tube and endometrial dysfunction, corresponding...

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Main Authors: Peter Jackuliak, Martin Jankovský, Magdaléna Kovářová, Jaroslav Voller, Claudia Feitscherová, Ivan Varga
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
diabetes mellitus
hyperglycaemia
infertility
endometrial receptivity
embryo-endometrium crosstalk
endometrial immune cell
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1582039/full
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