Antiarrhythmic and Hemodynamic Effects of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Diseases

This review presents the results of previously performed epidemiological, experimental and clinical studies indicating the use of ω-3 PUFA (polyunsaturated fatty acids) contributes to reduce the risk of developing cardiovascular diseases. Experimental studies have shown ω-3 PUFA are exhibiting antia...

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Main Authors: A. N. Zakirova, N. E. Zakirova
Format: Article
Language:English
Published: Столичная издательская компания 2022-05-01
Series:Рациональная фармакотерапия в кардиологии
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Online Access:https://www.rpcardio.online/jour/article/view/2717
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author A. N. Zakirova
N. E. Zakirova
author_facet A. N. Zakirova
N. E. Zakirova
author_sort A. N. Zakirova
collection DOAJ
description This review presents the results of previously performed epidemiological, experimental and clinical studies indicating the use of ω-3 PUFA (polyunsaturated fatty acids) contributes to reduce the risk of developing cardiovascular diseases. Experimental studies have shown ω-3 PUFA are exhibiting antiarrhythmic effects, improving endothelial function, showing an anti- inflammatory effect, affecting the rheological properties of blood, reducing triglyceride concentrations, and increasing the stability of atheromatous plaque. Wide-scale clinical trials have established high efficacy of ω-3 PUFA in primary and secondary prevention of coronary heart disease. It is found to reduce the risk of ventricular arrhythmias and sudden cardiac death. Also, reduces overall mortality and hospitalization rates due to cardiovascular causes in patients with chronic heart failure. Clinical efficacy among cardiovascular diseases of the prescription drugs ω-3 PUFA standardized by qualitative and quantitative compositions to be studied further in a comparison to the other medications with similar make-up.
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institution Kabale University
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language English
publishDate 2022-05-01
publisher Столичная издательская компания
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series Рациональная фармакотерапия в кардиологии
spelling doaj-art-5c8d06144f954dcc99b0b41e7bfdb16d2025-08-23T10:00:35ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532022-05-0118220921710.20996/1819-6446-2022-03-012012Antiarrhythmic and Hemodynamic Effects of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular DiseasesA. N. Zakirova0N. E. Zakirova1Bashkir State Medical UniversityBashkir State Medical UniversityThis review presents the results of previously performed epidemiological, experimental and clinical studies indicating the use of ω-3 PUFA (polyunsaturated fatty acids) contributes to reduce the risk of developing cardiovascular diseases. Experimental studies have shown ω-3 PUFA are exhibiting antiarrhythmic effects, improving endothelial function, showing an anti- inflammatory effect, affecting the rheological properties of blood, reducing triglyceride concentrations, and increasing the stability of atheromatous plaque. Wide-scale clinical trials have established high efficacy of ω-3 PUFA in primary and secondary prevention of coronary heart disease. It is found to reduce the risk of ventricular arrhythmias and sudden cardiac death. Also, reduces overall mortality and hospitalization rates due to cardiovascular causes in patients with chronic heart failure. Clinical efficacy among cardiovascular diseases of the prescription drugs ω-3 PUFA standardized by qualitative and quantitative compositions to be studied further in a comparison to the other medications with similar make-up.https://www.rpcardio.online/jour/article/view/2717ω-3 polyunsaturated fatty acidscardiovascular diseasesischemic heart diseasecardiac arrhythmiaschronic heart failure
spellingShingle A. N. Zakirova
N. E. Zakirova
Antiarrhythmic and Hemodynamic Effects of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Diseases
Рациональная фармакотерапия в кардиологии
ω-3 polyunsaturated fatty acids
cardiovascular diseases
ischemic heart disease
cardiac arrhythmias
chronic heart failure
title Antiarrhythmic and Hemodynamic Effects of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Diseases
title_full Antiarrhythmic and Hemodynamic Effects of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Diseases
title_fullStr Antiarrhythmic and Hemodynamic Effects of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Diseases
title_full_unstemmed Antiarrhythmic and Hemodynamic Effects of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Diseases
title_short Antiarrhythmic and Hemodynamic Effects of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Diseases
title_sort antiarrhythmic and hemodynamic effects of omega 3 polyunsaturated fatty acids on cardiovascular diseases
topic ω-3 polyunsaturated fatty acids
cardiovascular diseases
ischemic heart disease
cardiac arrhythmias
chronic heart failure
url https://www.rpcardio.online/jour/article/view/2717
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