Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction

Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction

The emergence of SARS-CoV-2 has led to the current global coronavirus pandemic and more than one million infections since December 2019. The exact origin of SARS-CoV-2 remains elusive, but the presence of a distinct motif in the S1/S2 junction region suggests the possible acquisition of cleavage sit...

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Bibliographic Details
Main Authors: Siu-Ying Lau, Pui Wang, Bobo Wing-Yee Mok, Anna Jinxia Zhang, Hin Chu, Andrew Chak-Yiu Lee, Shaofeng Deng, Pin Chen, Kwok-Hung Chan, Wenjun Song, Zhiwei Chen, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Honglin Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Coronavirus
COVID-19
SARS-CoV-2
Spike mutant
Spike S1/S2 mutant
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1756700
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