Pulmonary Hypertension Related to Left-Sided Cardiac Pathology
Pulmonary hypertension (PH) is the end result of a variety of diverse pathologic processes. The chronic elevation in pulmonary artery pressure often leads to right ventricular pressure overload and subsequent right ventricular failure. In patients with left-sided cardiac disease, PH is quite commo...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Pulmonary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/381787 |
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| _version_ | 1832556816105472000 |
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| author | Todd L. Kiefer Thomas M. Bashore |
| author_facet | Todd L. Kiefer Thomas M. Bashore |
| author_sort | Todd L. Kiefer |
| collection | DOAJ |
| description | Pulmonary hypertension (PH) is the end result of a variety of diverse pathologic processes. The chronic elevation in pulmonary artery pressure often leads to right ventricular pressure overload and subsequent right ventricular failure. In patients with left-sided cardiac disease, PH is quite common and associated with increased morbidity and mortality. This article will review the literature as it pertains to the epidemiology, pathogenesis, and diagnosis of PH related to aortic valve disease, mitral valve disease, left ventricular systolic and diastolic dysfunction, and pulmonary veno-occlusive disease. Moreover, therapeutic strategies, which focus on treating the underlying cardiac pathology will be discussed. |
| format | Article |
| id | doaj-art-5c81828d4e20422ab703df74edc3dd0f |
| institution | Kabale University |
| issn | 2090-1836 2090-1844 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Medicine |
| spelling | doaj-art-5c81828d4e20422ab703df74edc3dd0f2025-02-03T05:44:22ZengWileyPulmonary Medicine2090-18362090-18442011-01-01201110.1155/2011/381787381787Pulmonary Hypertension Related to Left-Sided Cardiac PathologyTodd L. Kiefer0Thomas M. Bashore1Division of Cardiology, Duke University Medical Center, P.O. Box 3102, Durham, NC 27710, USADivision of Cardiology, Duke University Medical Center, P.O. Box 3102, Durham, NC 27710, USAPulmonary hypertension (PH) is the end result of a variety of diverse pathologic processes. The chronic elevation in pulmonary artery pressure often leads to right ventricular pressure overload and subsequent right ventricular failure. In patients with left-sided cardiac disease, PH is quite common and associated with increased morbidity and mortality. This article will review the literature as it pertains to the epidemiology, pathogenesis, and diagnosis of PH related to aortic valve disease, mitral valve disease, left ventricular systolic and diastolic dysfunction, and pulmonary veno-occlusive disease. Moreover, therapeutic strategies, which focus on treating the underlying cardiac pathology will be discussed.http://dx.doi.org/10.1155/2011/381787 |
| spellingShingle | Todd L. Kiefer Thomas M. Bashore Pulmonary Hypertension Related to Left-Sided Cardiac Pathology Pulmonary Medicine |
| title | Pulmonary Hypertension Related to Left-Sided Cardiac Pathology |
| title_full | Pulmonary Hypertension Related to Left-Sided Cardiac Pathology |
| title_fullStr | Pulmonary Hypertension Related to Left-Sided Cardiac Pathology |
| title_full_unstemmed | Pulmonary Hypertension Related to Left-Sided Cardiac Pathology |
| title_short | Pulmonary Hypertension Related to Left-Sided Cardiac Pathology |
| title_sort | pulmonary hypertension related to left sided cardiac pathology |
| url | http://dx.doi.org/10.1155/2011/381787 |
| work_keys_str_mv | AT toddlkiefer pulmonaryhypertensionrelatedtoleftsidedcardiacpathology AT thomasmbashore pulmonaryhypertensionrelatedtoleftsidedcardiacpathology |