Selective Enrichment of Hypermethylated DNA by a Multivalent Binding Platform
Abstract The preselection of hypermethylated DNA (hmDNA) from liquid biopsy samples is key to enable early‐stage cancer diagnostics. Due to limited selectivity of the existing preselection approaches, however, wide integration in the clinic is currently prohibited. Here, it is argued that an affinit...
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| Main Authors: | Ruben W. Kolkman, Loes I. Segerink, Jurriaan Huskens |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2022-12-01
|
| Series: | Advanced Materials Interfaces |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/admi.202201557 |
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