Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B

Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B

Abstract Background Amphotericin is admixed to Polymethylmethacrylic (PMMA) spacers for fungal periprosthetic joint infections (PJI) during two-stage exchanges. We aimed to analyse the mechanical properties of PMMA cement with admixed Amphotericin B. Materials and methods We tested Amphotericin in P...

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Bibliographic Details
Main Authors: Florian A. Frank, Barbara Krampitz, Julia Steiner, Rainer Strathausen, Mario Morgenstern, Martin Clauss, Klaus-Dieter Kühn
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Amphotericin B
PMMA
Candida
Fungal PJI
ISO 5833
Online Access:https://doi.org/10.1186/s13018-025-05565-x
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