The complex journey of targeting RAS in oncology
Abstract Given the prevalence of RAS mutations in various cancers, personalized therapeutic approaches, guided by molecular markers, are essential. Farnesyltransferase inhibitors (FTIs) have emerged as potential therapeutic options; however, they also face obstacles such as toxicity and limited effi...
Saved in:
| Main Authors: | Katarzyna Wasiak, Damian Ciunowicz, Amelia Kierasińska-Kałka, Marta Węgierska, Marcin Pacholczyk, Piotr Rieske, Ewelina Stoczyńska-Fidelus |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
|
| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12885-025-14033-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer
by: M. P. Smal, et al.
Published: (2015-12-01) -
Molecular-genetic mechanisms of the signal cascade RAS-RAF-MEK-ERK associated with the development of the tumor process and the purpose of targeted drugs for colorectal cancer
by: A. N. Toropovsky, et al.
Published: (2021-08-01) -
A compilation of 13 patients with metastatic colorectal cancer and concomitant BRAF and RAS family mutations
by: Jigisha Srivastav, et al.
Published: (2025-08-01) -
Eosinophilic Cells as a Distinct Morphological Feature in <i>BRAF<sup>V600E</sup></i>-Mutated Ovarian Serous Borderline Tumors
by: Alina Badlaeva, et al.
Published: (2025-06-01) -
Distinct association of HRAS and KRAS with Mn2+ ion illustrated by paramagnetic NMR
by: Jia-Liang Chen, et al.
Published: (2025-02-01)