Synovitis in osteoarthritis: the current state of the problem

The article presents current data on synovitis (inflammation of the synovial membrane), which is often the only clinical manifestation of osteoarthritis (OA), and considered to be one of the risk factors for the OA development. Synovitis severity correlates with the severity of OA symptoms. The asse...

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Main Authors: I. S. Dydykina, E. V. Arutyunova, P. S. Kovalenko, E. V. Nikolaeva, A. V. Naumov
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2021-04-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/1132
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author I. S. Dydykina
E. V. Arutyunova
P. S. Kovalenko
E. V. Nikolaeva
A. V. Naumov
author_facet I. S. Dydykina
E. V. Arutyunova
P. S. Kovalenko
E. V. Nikolaeva
A. V. Naumov
author_sort I. S. Dydykina
collection DOAJ
description The article presents current data on synovitis (inflammation of the synovial membrane), which is often the only clinical manifestation of osteoarthritis (OA), and considered to be one of the risk factors for the OA development. Synovitis severity correlates with the severity of OA symptoms. The assessment of the prevalence of synovitis presents significant difficulties and depends on the nature and severity of the disease, the cohort in question, diagnostic method, and therapy. The classification based on etiological, clinical and histological characteristics of synovitis is presented. Examination of synovial tissue characteristics and its changes during inflammatory response can significantly expand the possibilities for therapy and prognosis. The use of symptomatic delayed-action drugs (SYSADOA) is considered as the basic treatment of OA. Chondroitin sulfate (Chondroquard®) is one of the well established drugs, it has symptom- and structural-modifying properties. The article presents the results of studies confirming its effectiveness in reducing the severity of knee synovitis.
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institution Kabale University
issn 1996-7012
2310-158X
language Russian
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series Современная ревматология
spelling doaj-art-5c611d6e84d345b282ff2cb640146e8a2025-08-20T03:44:10ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2021-04-0115212012510.14412/1996-7012-2021-2-120-1252353Synovitis in osteoarthritis: the current state of the problemI. S. Dydykina0E. V. Arutyunova1P. S. Kovalenko2E. V. Nikolaeva3A. V. Naumov4V.A. Nasonova Research Institute of RheumatologyM.V. Lomonosov Moscow State UniversityV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyRussian Clinical and Research Center of Gerontology, N.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaThe article presents current data on synovitis (inflammation of the synovial membrane), which is often the only clinical manifestation of osteoarthritis (OA), and considered to be one of the risk factors for the OA development. Synovitis severity correlates with the severity of OA symptoms. The assessment of the prevalence of synovitis presents significant difficulties and depends on the nature and severity of the disease, the cohort in question, diagnostic method, and therapy. The classification based on etiological, clinical and histological characteristics of synovitis is presented. Examination of synovial tissue characteristics and its changes during inflammatory response can significantly expand the possibilities for therapy and prognosis. The use of symptomatic delayed-action drugs (SYSADOA) is considered as the basic treatment of OA. Chondroitin sulfate (Chondroquard®) is one of the well established drugs, it has symptom- and structural-modifying properties. The article presents the results of studies confirming its effectiveness in reducing the severity of knee synovitis.https://mrj.ima-press.net/mrj/article/view/1132osteoarthritisknee osteoarthritissynovial membranesynovitisdiagnosis of synovitisclassification of synovitistreatment of synovitischondroquard®
spellingShingle I. S. Dydykina
E. V. Arutyunova
P. S. Kovalenko
E. V. Nikolaeva
A. V. Naumov
Synovitis in osteoarthritis: the current state of the problem
Современная ревматология
osteoarthritis
knee osteoarthritis
synovial membrane
synovitis
diagnosis of synovitis
classification of synovitis
treatment of synovitis
chondroquard®
title Synovitis in osteoarthritis: the current state of the problem
title_full Synovitis in osteoarthritis: the current state of the problem
title_fullStr Synovitis in osteoarthritis: the current state of the problem
title_full_unstemmed Synovitis in osteoarthritis: the current state of the problem
title_short Synovitis in osteoarthritis: the current state of the problem
title_sort synovitis in osteoarthritis the current state of the problem
topic osteoarthritis
knee osteoarthritis
synovial membrane
synovitis
diagnosis of synovitis
classification of synovitis
treatment of synovitis
chondroquard®
url https://mrj.ima-press.net/mrj/article/view/1132
work_keys_str_mv AT isdydykina synovitisinosteoarthritisthecurrentstateoftheproblem
AT evarutyunova synovitisinosteoarthritisthecurrentstateoftheproblem
AT pskovalenko synovitisinosteoarthritisthecurrentstateoftheproblem
AT evnikolaeva synovitisinosteoarthritisthecurrentstateoftheproblem
AT avnaumov synovitisinosteoarthritisthecurrentstateoftheproblem