Intelligence Deficits in Chinese Patients with Brain Tumor: The Impact of Tumor Resection

Background. Intelligence is much important for brain tumor patients after their operation, while the reports about surgical related intelligence deficits are not frequent. It is not only theoretically important but also meaningful for clinical practice. Methods. Wechsler Adult Intelligence Scale was...

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Main Authors: Chao Shen, Rong Xie, Xiaoyun Cao, Weimin Bao, Bojie Yang, Ying Mao, Chao Gao
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/261236
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author Chao Shen
Rong Xie
Xiaoyun Cao
Weimin Bao
Bojie Yang
Ying Mao
Chao Gao
author_facet Chao Shen
Rong Xie
Xiaoyun Cao
Weimin Bao
Bojie Yang
Ying Mao
Chao Gao
author_sort Chao Shen
collection DOAJ
description Background. Intelligence is much important for brain tumor patients after their operation, while the reports about surgical related intelligence deficits are not frequent. It is not only theoretically important but also meaningful for clinical practice. Methods. Wechsler Adult Intelligence Scale was employed to evaluate the intelligence of 103 patients with intracranial tumor and to compare the intelligence quotient (IQ), verbal IQ (VIQ), and performance IQ (PIQ) between the intracerebral and extracerebral subgroups. Results. Although preoperative intelligence deficits appeared in all subgroups, IQ, VIQ, and PIQ were not found to have any significant difference between the intracerebral and extracerebral subgroups, but with VIQ lower than PIQ in all the subgroups. An immediate postoperative follow-up demonstrated a decline of IQ and PIQ in the extracerebral subgroup, but an improvement of VIQ in the right intracerebral subgroup. Pituitary adenoma resection exerted no effect on intelligence. In addition, age, years of education, and tumor size were found to play important roles. Conclusions. Brain tumors will impair IQ, VIQ, and PIQ. The extracerebral tumor resection can deteriorate IQ and PIQ. However, right intracerebral tumor resection is beneficial to VIQ, and transsphenoidal pituitary adenoma resection performs no effect on intelligence.
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spelling doaj-art-5c5cf60e08c541a28c47ae6d146e80b12025-08-20T02:05:43ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/261236261236Intelligence Deficits in Chinese Patients with Brain Tumor: The Impact of Tumor ResectionChao Shen0Rong Xie1Xiaoyun Cao2Weimin Bao3Bojie Yang4Ying Mao5Chao Gao6Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, ChinaInstitute of Neurology, Fudan University, Shanghai 200040, ChinaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, ChinaInstitute of Neurology, Fudan University, Shanghai 200040, ChinaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, ChinaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, ChinaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, ChinaBackground. Intelligence is much important for brain tumor patients after their operation, while the reports about surgical related intelligence deficits are not frequent. It is not only theoretically important but also meaningful for clinical practice. Methods. Wechsler Adult Intelligence Scale was employed to evaluate the intelligence of 103 patients with intracranial tumor and to compare the intelligence quotient (IQ), verbal IQ (VIQ), and performance IQ (PIQ) between the intracerebral and extracerebral subgroups. Results. Although preoperative intelligence deficits appeared in all subgroups, IQ, VIQ, and PIQ were not found to have any significant difference between the intracerebral and extracerebral subgroups, but with VIQ lower than PIQ in all the subgroups. An immediate postoperative follow-up demonstrated a decline of IQ and PIQ in the extracerebral subgroup, but an improvement of VIQ in the right intracerebral subgroup. Pituitary adenoma resection exerted no effect on intelligence. In addition, age, years of education, and tumor size were found to play important roles. Conclusions. Brain tumors will impair IQ, VIQ, and PIQ. The extracerebral tumor resection can deteriorate IQ and PIQ. However, right intracerebral tumor resection is beneficial to VIQ, and transsphenoidal pituitary adenoma resection performs no effect on intelligence.http://dx.doi.org/10.1155/2013/261236
spellingShingle Chao Shen
Rong Xie
Xiaoyun Cao
Weimin Bao
Bojie Yang
Ying Mao
Chao Gao
Intelligence Deficits in Chinese Patients with Brain Tumor: The Impact of Tumor Resection
The Scientific World Journal
title Intelligence Deficits in Chinese Patients with Brain Tumor: The Impact of Tumor Resection
title_full Intelligence Deficits in Chinese Patients with Brain Tumor: The Impact of Tumor Resection
title_fullStr Intelligence Deficits in Chinese Patients with Brain Tumor: The Impact of Tumor Resection
title_full_unstemmed Intelligence Deficits in Chinese Patients with Brain Tumor: The Impact of Tumor Resection
title_short Intelligence Deficits in Chinese Patients with Brain Tumor: The Impact of Tumor Resection
title_sort intelligence deficits in chinese patients with brain tumor the impact of tumor resection
url http://dx.doi.org/10.1155/2013/261236
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