The Toxic and Pathophysiological Aspects of Smoking Related to the Most Usual Forms of Use and Exposure to Tobacco Smoke – A Systematic Review

This review aimed to delineate the toxicity and pathogenicity of conventional, electronic, and hookah cigarettes concerning active and passive smoking, bringing epidemiological aspects related to Brazil. The research, conducted on the descriptors "nicotine extraction", "nicotine and...

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Main Authors: Isadora de Jesus Mariano Lacerda, Cinthia Eloise Domingues
Format: Article
Language:English
Published: Universidade Federal de Mato Grosso do Sul 2025-05-01
Series:Orbital: The Electronic Journal of Chemistry
Subjects:
Online Access:https://trilhasdahistoria.ufms.br/index.php/orbital/article/view/19704
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author Isadora de Jesus Mariano Lacerda
Cinthia Eloise Domingues
author_facet Isadora de Jesus Mariano Lacerda
Cinthia Eloise Domingues
author_sort Isadora de Jesus Mariano Lacerda
collection DOAJ
description This review aimed to delineate the toxicity and pathogenicity of conventional, electronic, and hookah cigarettes concerning active and passive smoking, bringing epidemiological aspects related to Brazil. The research, conducted on the descriptors "nicotine extraction", "nicotine and toxicology", and "smoking and pathophysiology" in the Science Direct, Pubmed, Scopus, and Web of Science databases, resulted in the selection of 28 articles (2010-2022). Outside, also, exposed by the IBGE System of Automatic Recovery (SIDRA) in association with the National Health Survey (PNS), the percentages related to national smoking. It was found that the main affected systems are immunological, respiratory, and cardiovascular, with occurrences of cytotoxicity and genotoxicity, factors that are associated mainly with the presence of nicotine and toxic metabolites in cigarette smoke. It was also shown that levels of heavy metals can be found in e-cigarettes and that hookah. Conventional cigarettes still are the most harmful form of smoking. It is seen that indirect smoke stands for a serious public health problem because 80% of nitrosamines deposited on surfaces are not removed under normal ventilation conditions. It is concluded that smoking, regardless of the form of exposure, is harmful to the biological system, directly and indirectly affecting essential organs for human survival.
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spelling doaj-art-5c47c73f137b416a99221c2fededadde2025-08-20T02:26:14ZengUniversidade Federal de Mato Grosso do SulOrbital: The Electronic Journal of Chemistry1984-64282025-05-0117210.17807/orbital.v17i2.19704The Toxic and Pathophysiological Aspects of Smoking Related to the Most Usual Forms of Use and Exposure to Tobacco Smoke – A Systematic ReviewIsadora de Jesus Mariano Lacerda0Cinthia Eloise Domingues1UniCesumar, Department of Biological and Health SciencesUniCesumar, Department of Biological and Health Sciences This review aimed to delineate the toxicity and pathogenicity of conventional, electronic, and hookah cigarettes concerning active and passive smoking, bringing epidemiological aspects related to Brazil. The research, conducted on the descriptors "nicotine extraction", "nicotine and toxicology", and "smoking and pathophysiology" in the Science Direct, Pubmed, Scopus, and Web of Science databases, resulted in the selection of 28 articles (2010-2022). Outside, also, exposed by the IBGE System of Automatic Recovery (SIDRA) in association with the National Health Survey (PNS), the percentages related to national smoking. It was found that the main affected systems are immunological, respiratory, and cardiovascular, with occurrences of cytotoxicity and genotoxicity, factors that are associated mainly with the presence of nicotine and toxic metabolites in cigarette smoke. It was also shown that levels of heavy metals can be found in e-cigarettes and that hookah. Conventional cigarettes still are the most harmful form of smoking. It is seen that indirect smoke stands for a serious public health problem because 80% of nitrosamines deposited on surfaces are not removed under normal ventilation conditions. It is concluded that smoking, regardless of the form of exposure, is harmful to the biological system, directly and indirectly affecting essential organs for human survival. https://trilhasdahistoria.ufms.br/index.php/orbital/article/view/19704Conventional cigaretteElectronic cigaretteHookahPathogenicityToxicity
spellingShingle Isadora de Jesus Mariano Lacerda
Cinthia Eloise Domingues
The Toxic and Pathophysiological Aspects of Smoking Related to the Most Usual Forms of Use and Exposure to Tobacco Smoke – A Systematic Review
Orbital: The Electronic Journal of Chemistry
Conventional cigarette
Electronic cigarette
Hookah
Pathogenicity
Toxicity
title The Toxic and Pathophysiological Aspects of Smoking Related to the Most Usual Forms of Use and Exposure to Tobacco Smoke – A Systematic Review
title_full The Toxic and Pathophysiological Aspects of Smoking Related to the Most Usual Forms of Use and Exposure to Tobacco Smoke – A Systematic Review
title_fullStr The Toxic and Pathophysiological Aspects of Smoking Related to the Most Usual Forms of Use and Exposure to Tobacco Smoke – A Systematic Review
title_full_unstemmed The Toxic and Pathophysiological Aspects of Smoking Related to the Most Usual Forms of Use and Exposure to Tobacco Smoke – A Systematic Review
title_short The Toxic and Pathophysiological Aspects of Smoking Related to the Most Usual Forms of Use and Exposure to Tobacco Smoke – A Systematic Review
title_sort toxic and pathophysiological aspects of smoking related to the most usual forms of use and exposure to tobacco smoke a systematic review
topic Conventional cigarette
Electronic cigarette
Hookah
Pathogenicity
Toxicity
url https://trilhasdahistoria.ufms.br/index.php/orbital/article/view/19704
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