Neuropsychiatric and Physical Manifestations of Post-Covid-19 Syndrome: Insights into Physical Activity and Biomarkers in the Moroccan Population
Several patients experience persistent symptoms that last for more than three months following the acute phase of SARS-CoV-2 infection. These symptoms, which cannot be attributed to any other diagnosis, are collectively referred to as post-Covid-19 syndrome. This study aimed to physiologically char...
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Institut des Sciences du Sport, Université Hassan Premier de Settat
2025-01-01
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| Series: | Réflexions Sportives |
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| Online Access: | https://revues.imist.ma/index.php/RefSport/article/view/54002 |
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| author | Youssef NADIR Habiba NECHCHADI Hicham ESSELMANI Mohamed MERZOUKI Karim ARIFI |
| author_facet | Youssef NADIR Habiba NECHCHADI Hicham ESSELMANI Mohamed MERZOUKI Karim ARIFI |
| author_sort | Youssef NADIR |
| collection | DOAJ |
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Several patients experience persistent symptoms that last for more than three months following the acute phase of SARS-CoV-2 infection. These symptoms, which cannot be attributed to any other diagnosis, are collectively referred to as post-Covid-19 syndrome. This study aimed to physiologically characterize Moroccan patients with post-Covid-19 syndrome, determine the prevalence of five persistent neuropsychiatric and physical manifestations, and analyze the factors associated with these symptoms. We conducted a cross-sectional study of 120 patients with post-Covid-19 syndrome in the province of Beni Mellal, Morocco. Descriptive statistics were used to summarize sociodemographic and clinical characteristics, Covid-19 status, pre-infection physical activity level. Logistic regression was used to study associations between pre-infection physical activity level and biomarkers with the manifestations of post-Covid-19 syndrome. No association was found between the level of physical activity and neuropsychiatric and physical manifestations of post-Covid-19 syndrome. When comparing the mean LDL- cholesterol concentration with pre-infection physical activity level, a significant difference was detected (P = 0.0437). The same result was observed when the HDL cholesterol concentration was compared according to sex (P = 0.0024). Fatigue was the most common symptom in the study population (67%), whereas depression was the least common symptom (10%). The logistic regression model revealed a negative association between HDL cholesterol levels and dyspnea (P = 0.0472). Pre-infection physical activity levels may influence LDL-cholesterol concentrations in post-Covid-19 syndrome patients. Lower HDL-cholesterol concentration may be linked to the persistence of dyspnea, which makes it a potential biomarker; further mechanistic investigations are needed taking gender differences into consideration.
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| format | Article |
| id | doaj-art-5c3c6e44bf6840bea3e3b388519642bf |
| institution | Kabale University |
| issn | 2737-8799 |
| language | Arabic |
| publishDate | 2025-01-01 |
| publisher | Institut des Sciences du Sport, Université Hassan Premier de Settat |
| record_format | Article |
| series | Réflexions Sportives |
| spelling | doaj-art-5c3c6e44bf6840bea3e3b388519642bf2025-01-11T22:14:02ZaraInstitut des Sciences du Sport, Université Hassan Premier de SettatRéflexions Sportives2737-87992025-01-01410.34874/IMIST.PRSM/refsport-i4.54002Neuropsychiatric and Physical Manifestations of Post-Covid-19 Syndrome: Insights into Physical Activity and Biomarkers in the Moroccan PopulationYoussef NADIRhttps://orcid.org/0009-0007-4089-0860Habiba NECHCHADIhttps://orcid.org/0000-0002-9805-4917Hicham ESSELMANIhttps://orcid.org/0000-0001-7074-3369Mohamed MERZOUKIhttps://orcid.org/0000-0002-9837-4312Karim ARIFIhttps://orcid.org/0000-0002-0441-6850 Several patients experience persistent symptoms that last for more than three months following the acute phase of SARS-CoV-2 infection. These symptoms, which cannot be attributed to any other diagnosis, are collectively referred to as post-Covid-19 syndrome. This study aimed to physiologically characterize Moroccan patients with post-Covid-19 syndrome, determine the prevalence of five persistent neuropsychiatric and physical manifestations, and analyze the factors associated with these symptoms. We conducted a cross-sectional study of 120 patients with post-Covid-19 syndrome in the province of Beni Mellal, Morocco. Descriptive statistics were used to summarize sociodemographic and clinical characteristics, Covid-19 status, pre-infection physical activity level. Logistic regression was used to study associations between pre-infection physical activity level and biomarkers with the manifestations of post-Covid-19 syndrome. No association was found between the level of physical activity and neuropsychiatric and physical manifestations of post-Covid-19 syndrome. When comparing the mean LDL- cholesterol concentration with pre-infection physical activity level, a significant difference was detected (P = 0.0437). The same result was observed when the HDL cholesterol concentration was compared according to sex (P = 0.0024). Fatigue was the most common symptom in the study population (67%), whereas depression was the least common symptom (10%). The logistic regression model revealed a negative association between HDL cholesterol levels and dyspnea (P = 0.0472). Pre-infection physical activity levels may influence LDL-cholesterol concentrations in post-Covid-19 syndrome patients. Lower HDL-cholesterol concentration may be linked to the persistence of dyspnea, which makes it a potential biomarker; further mechanistic investigations are needed taking gender differences into consideration. https://revues.imist.ma/index.php/RefSport/article/view/54002Post-Covid-19 syndromePhysical activityMental healthInflammationLipid metabolism |
| spellingShingle | Youssef NADIR Habiba NECHCHADI Hicham ESSELMANI Mohamed MERZOUKI Karim ARIFI Neuropsychiatric and Physical Manifestations of Post-Covid-19 Syndrome: Insights into Physical Activity and Biomarkers in the Moroccan Population Réflexions Sportives Post-Covid-19 syndrome Physical activity Mental health Inflammation Lipid metabolism |
| title | Neuropsychiatric and Physical Manifestations of Post-Covid-19 Syndrome: Insights into Physical Activity and Biomarkers in the Moroccan Population |
| title_full | Neuropsychiatric and Physical Manifestations of Post-Covid-19 Syndrome: Insights into Physical Activity and Biomarkers in the Moroccan Population |
| title_fullStr | Neuropsychiatric and Physical Manifestations of Post-Covid-19 Syndrome: Insights into Physical Activity and Biomarkers in the Moroccan Population |
| title_full_unstemmed | Neuropsychiatric and Physical Manifestations of Post-Covid-19 Syndrome: Insights into Physical Activity and Biomarkers in the Moroccan Population |
| title_short | Neuropsychiatric and Physical Manifestations of Post-Covid-19 Syndrome: Insights into Physical Activity and Biomarkers in the Moroccan Population |
| title_sort | neuropsychiatric and physical manifestations of post covid 19 syndrome insights into physical activity and biomarkers in the moroccan population |
| topic | Post-Covid-19 syndrome Physical activity Mental health Inflammation Lipid metabolism |
| url | https://revues.imist.ma/index.php/RefSport/article/view/54002 |
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