Quantitative analysis of multi-components by single marker—a rational method for the internal quality of Chinese herbal medicine
In order to achieve the comprehensive quality control of Chinese herbal medicine (CHM), the conventional practice of selecting a single marker for testing has been gradually replaced by the determination of multiple active components based on the characteristics of the synergistic interaction of CHM...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-03-01
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| Series: | Integrative Medicine Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213422016301421 |
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| author | Chunsheng Zhu Xiaoping Li Bing Zhang Zhijian Lin |
| author_facet | Chunsheng Zhu Xiaoping Li Bing Zhang Zhijian Lin |
| author_sort | Chunsheng Zhu |
| collection | DOAJ |
| description | In order to achieve the comprehensive quality control of Chinese herbal medicine (CHM), the conventional practice of selecting a single marker for testing has been gradually replaced by the determination of multiple active components based on the characteristics of the synergistic interaction of CHM and applicability of sophisticated analytical techniques. However, with a huge number of CHM in the market and more complex preparations, the limited availability of various standard substances for quantitative analysis has been a major bottleneck in realizing the goal. To overcome these uprising problems, quantitative analysis of multi-components by single marker (QAMS) was proposed and accepted as a new method to reflect the internal quality of CHM. In this review, the current knowledge about QAMS is systematically summarized, including the general content of QAMS, current status, and general procedure. Additionally, speculation is proposed about the future applications of QAMS approaches in the modernization and standardization of CHM. |
| format | Article |
| id | doaj-art-5c2d6efdd3d84630b551df1b33a241b3 |
| institution | OA Journals |
| issn | 2213-4220 |
| language | English |
| publishDate | 2017-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Integrative Medicine Research |
| spelling | doaj-art-5c2d6efdd3d84630b551df1b33a241b32025-08-20T02:28:09ZengElsevierIntegrative Medicine Research2213-42202017-03-016111110.1016/j.imr.2017.01.008Quantitative analysis of multi-components by single marker—a rational method for the internal quality of Chinese herbal medicineChunsheng Zhu0Xiaoping Li1Bing Zhang2Zhijian Lin3The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaThe First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, ChinaIn order to achieve the comprehensive quality control of Chinese herbal medicine (CHM), the conventional practice of selecting a single marker for testing has been gradually replaced by the determination of multiple active components based on the characteristics of the synergistic interaction of CHM and applicability of sophisticated analytical techniques. However, with a huge number of CHM in the market and more complex preparations, the limited availability of various standard substances for quantitative analysis has been a major bottleneck in realizing the goal. To overcome these uprising problems, quantitative analysis of multi-components by single marker (QAMS) was proposed and accepted as a new method to reflect the internal quality of CHM. In this review, the current knowledge about QAMS is systematically summarized, including the general content of QAMS, current status, and general procedure. Additionally, speculation is proposed about the future applications of QAMS approaches in the modernization and standardization of CHM.http://www.sciencedirect.com/science/article/pii/S2213422016301421Chinese herbal medicinequantitative analysis of multi-components by single markerrelative correction factor |
| spellingShingle | Chunsheng Zhu Xiaoping Li Bing Zhang Zhijian Lin Quantitative analysis of multi-components by single marker—a rational method for the internal quality of Chinese herbal medicine Integrative Medicine Research Chinese herbal medicine quantitative analysis of multi-components by single marker relative correction factor |
| title | Quantitative analysis of multi-components by single marker—a rational method for the internal quality of Chinese herbal medicine |
| title_full | Quantitative analysis of multi-components by single marker—a rational method for the internal quality of Chinese herbal medicine |
| title_fullStr | Quantitative analysis of multi-components by single marker—a rational method for the internal quality of Chinese herbal medicine |
| title_full_unstemmed | Quantitative analysis of multi-components by single marker—a rational method for the internal quality of Chinese herbal medicine |
| title_short | Quantitative analysis of multi-components by single marker—a rational method for the internal quality of Chinese herbal medicine |
| title_sort | quantitative analysis of multi components by single marker a rational method for the internal quality of chinese herbal medicine |
| topic | Chinese herbal medicine quantitative analysis of multi-components by single marker relative correction factor |
| url | http://www.sciencedirect.com/science/article/pii/S2213422016301421 |
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