Structural basis of human cytomegalovirus neutralization by gB AD-5-specific potent antibodies

Structural basis of human cytomegalovirus neutralization by gB AD-5-specific potent antibodies

Summary: Human cytomegalovirus (hCMV) poses a severe threat to fetuses, newborns, and immunocompromised individuals. No approved vaccines and limited treatment options are current medical challenges. Here, we analyze the human B cell responses to glycoprotein B (gB) in three top hCMV neutralizers fr...

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Main Authors: Changwen Wu, Nan Song, Yizhen Zhao, Han Wang, Yuanbao Ai, Yayu Wang, Yueming Wang, Xiaohui Yuan, Tong Liu, Nan Li, Dabbu Kumar Jaijyan, Chengming Li, Lei Zhang, Weihong Zheng, Zhiwei Yang, Shujia Zhu, Hua-Xin Liao
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725004176
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