Relationship between presenting symptoms and tumor location in colorectal cancer patients

Background Colorectal cancer (CRC) often shows symptoms at an advanced stage, causing delayed diagnosis and poorer prognosis. Initial symptoms, or chief complaints, are usually identified through patient history and can vary based on tumor location. This can help in establishing a diagnosis. This s...

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Main Authors: Fitri Dewi Ismida, Desi Maghfirah, Nurbahri L Salam, Fauzi Yusuf, Vera Dewi Mulia, Avisena Gatot Purnomo
Format: Article
Language:English
Published: Faculty of Medicine Trisakti University 2024-12-01
Series:Universa Medicina
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Online Access:https://univmed.org/ejurnal/index.php/medicina/article/view/1600
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author Fitri Dewi Ismida
Desi Maghfirah
Nurbahri L Salam
Fauzi Yusuf
Vera Dewi Mulia
Avisena Gatot Purnomo
author_facet Fitri Dewi Ismida
Desi Maghfirah
Nurbahri L Salam
Fauzi Yusuf
Vera Dewi Mulia
Avisena Gatot Purnomo
author_sort Fitri Dewi Ismida
collection DOAJ
description Background Colorectal cancer (CRC) often shows symptoms at an advanced stage, causing delayed diagnosis and poorer prognosis. Initial symptoms, or chief complaints, are usually identified through patient history and can vary based on tumor location. This can help in establishing a diagnosis. This study aimed to determine the relationship between presenting symptoms and tumor location in CRC patients at Zainoel Abidin Regional General Hospital, Banda Aceh. Methods This cross-sectional study was conducted using secondary data from medical records (2019–2022) for 163 CRC patients. Information on symptoms of patients were collected from patient files: anemia, anorexia, diarrhea, constipation, abdominal pain, rectal bleeding, and palpable abdominal mass. Tumor locations were classified as right colon, left colon, rectum, and left colon plus rectum. Bivariate analysis was used to analyze the data. Results Of the 163 patients, 98 (58%) were aged e”50 years, 82 (50.3%) were male, and 99 (60.7%) had rectal tumors. The percentage of patients presenting with rectal bleeding was significantly higher in rectal cancers (47.47%) as compared with cancers in the left colon (28.57%) and left colon and rectal (33.33%) cancers (p=0.000). The percentage of patients presenting a palpable abdominal mass was significantly higher in right colon (31.58%) compared with left colon (4.76%) and rectal cancer (1.01%) (p=0.000). Conclusions Tumor location in the right colon is associated with palpable abdominal mass, while rectal location is associated with rectal bleeding in CRC patients. Familiarity with clinical symptoms of CRC could make patients more sensitive to undergo more frequent screening for cancer.
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spelling doaj-art-5c1f5b6d88e643d98e16727e1b344ec62025-08-20T02:49:55ZengFaculty of Medicine Trisakti UniversityUniversa Medicina2407-22301907-30622024-12-0143310.18051/UnivMed.2024.v43.321-328Relationship between presenting symptoms and tumor location in colorectal cancer patientsFitri Dewi Ismida0Desi Maghfirah1Nurbahri L Salam2Fauzi Yusuf3Vera Dewi Mulia4Avisena Gatot Purnomo5Department of Anatomical Pathology, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, IndonesiaGastroenterohepatology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia Bachelor of Medicine Program, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, IndonesiaGastroenterohepatology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia Department of Anatomical Pathology, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, IndonesiaDepartment of Surgery, Meuraxa Hospital, Banda Aceh, Indonesia Background Colorectal cancer (CRC) often shows symptoms at an advanced stage, causing delayed diagnosis and poorer prognosis. Initial symptoms, or chief complaints, are usually identified through patient history and can vary based on tumor location. This can help in establishing a diagnosis. This study aimed to determine the relationship between presenting symptoms and tumor location in CRC patients at Zainoel Abidin Regional General Hospital, Banda Aceh. Methods This cross-sectional study was conducted using secondary data from medical records (2019–2022) for 163 CRC patients. Information on symptoms of patients were collected from patient files: anemia, anorexia, diarrhea, constipation, abdominal pain, rectal bleeding, and palpable abdominal mass. Tumor locations were classified as right colon, left colon, rectum, and left colon plus rectum. Bivariate analysis was used to analyze the data. Results Of the 163 patients, 98 (58%) were aged e”50 years, 82 (50.3%) were male, and 99 (60.7%) had rectal tumors. The percentage of patients presenting with rectal bleeding was significantly higher in rectal cancers (47.47%) as compared with cancers in the left colon (28.57%) and left colon and rectal (33.33%) cancers (p=0.000). The percentage of patients presenting a palpable abdominal mass was significantly higher in right colon (31.58%) compared with left colon (4.76%) and rectal cancer (1.01%) (p=0.000). Conclusions Tumor location in the right colon is associated with palpable abdominal mass, while rectal location is associated with rectal bleeding in CRC patients. Familiarity with clinical symptoms of CRC could make patients more sensitive to undergo more frequent screening for cancer. https://univmed.org/ejurnal/index.php/medicina/article/view/1600Tumor locationsymptomsrectal bleedingpalpable abdominal masscolorectal cancer
spellingShingle Fitri Dewi Ismida
Desi Maghfirah
Nurbahri L Salam
Fauzi Yusuf
Vera Dewi Mulia
Avisena Gatot Purnomo
Relationship between presenting symptoms and tumor location in colorectal cancer patients
Universa Medicina
Tumor location
symptoms
rectal bleeding
palpable abdominal mass
colorectal cancer
title Relationship between presenting symptoms and tumor location in colorectal cancer patients
title_full Relationship between presenting symptoms and tumor location in colorectal cancer patients
title_fullStr Relationship between presenting symptoms and tumor location in colorectal cancer patients
title_full_unstemmed Relationship between presenting symptoms and tumor location in colorectal cancer patients
title_short Relationship between presenting symptoms and tumor location in colorectal cancer patients
title_sort relationship between presenting symptoms and tumor location in colorectal cancer patients
topic Tumor location
symptoms
rectal bleeding
palpable abdominal mass
colorectal cancer
url https://univmed.org/ejurnal/index.php/medicina/article/view/1600
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