Detection of autoimmune thyroid diseases in patients with celiac disease

        Celiac disease is an autoimmune disorder induced by gluten intake in genetically susceptible individuals. The incidence of celiac disease in various autoimmune disorders is increased 10-30 fold in comparison to the general population and the prevalence of celiac disease was noted to be 2-5%...

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Main Authors: Rana S. Aboud, Haidar J. Mohammad, Nawal M. Jawad
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2009-09-01
Series:مجلة بغداد للعلوم
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Online Access:https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11885
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author Rana S. Aboud
Haidar J. Mohammad
Nawal M. Jawad
author_facet Rana S. Aboud
Haidar J. Mohammad
Nawal M. Jawad
author_sort Rana S. Aboud
collection DOAJ
description         Celiac disease is an autoimmune disorder induced by gluten intake in genetically susceptible individuals. The incidence of celiac disease in various autoimmune disorders is increased 10-30 fold in comparison to the general population and the prevalence of celiac disease was noted to be 2-5% in autoimmune thyroid disease. To detect the autoimmune thyroid disease in patients with celiac disease, we investigated 22 patients suspected with celiac disease of age 1-13 years old and 20 healthy controls. IgA and IgG antigliadin antibodies were measured in serum with celiac disease sample. The patients which were positive to gliadin antibody were carried out to T3, T4 and TSH by ELISA tests. There was no significant differences (P>0.05) in age group and gender of patients afflicted with celiac disease and there was highly significant deferances (P<0.01) with increased mean level of IgG antibody in sera of hyperthyroidism patients afflicted with celiac disease than normal group. We found a relationship between celiac disease and hyperthyroidism in patients. The aim of this study was to detect the autoimmune thyroid disease in patients with celiac disease. 
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series مجلة بغداد للعلوم
spelling doaj-art-5c1ae02898f24923a2bf62635fb112312025-08-20T03:56:18ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862009-09-016310.21123/bsj.2009.11885Detection of autoimmune thyroid diseases in patients with celiac diseaseRana S. AboudHaidar J. MohammadNawal M. Jawad         Celiac disease is an autoimmune disorder induced by gluten intake in genetically susceptible individuals. The incidence of celiac disease in various autoimmune disorders is increased 10-30 fold in comparison to the general population and the prevalence of celiac disease was noted to be 2-5% in autoimmune thyroid disease. To detect the autoimmune thyroid disease in patients with celiac disease, we investigated 22 patients suspected with celiac disease of age 1-13 years old and 20 healthy controls. IgA and IgG antigliadin antibodies were measured in serum with celiac disease sample. The patients which were positive to gliadin antibody were carried out to T3, T4 and TSH by ELISA tests. There was no significant differences (P>0.05) in age group and gender of patients afflicted with celiac disease and there was highly significant deferances (P<0.01) with increased mean level of IgG antibody in sera of hyperthyroidism patients afflicted with celiac disease than normal group. We found a relationship between celiac disease and hyperthyroidism in patients. The aim of this study was to detect the autoimmune thyroid disease in patients with celiac disease.  https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11885Celiac disease, IgA and IgG antigliadin Abs and T3, T4, TSH hormones
spellingShingle Rana S. Aboud
Haidar J. Mohammad
Nawal M. Jawad
Detection of autoimmune thyroid diseases in patients with celiac disease
مجلة بغداد للعلوم
Celiac disease, IgA and IgG antigliadin Abs and T3, T4, TSH hormones
title Detection of autoimmune thyroid diseases in patients with celiac disease
title_full Detection of autoimmune thyroid diseases in patients with celiac disease
title_fullStr Detection of autoimmune thyroid diseases in patients with celiac disease
title_full_unstemmed Detection of autoimmune thyroid diseases in patients with celiac disease
title_short Detection of autoimmune thyroid diseases in patients with celiac disease
title_sort detection of autoimmune thyroid diseases in patients with celiac disease
topic Celiac disease, IgA and IgG antigliadin Abs and T3, T4, TSH hormones
url https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11885
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AT haidarjmohammad detectionofautoimmunethyroiddiseasesinpatientswithceliacdisease
AT nawalmjawad detectionofautoimmunethyroiddiseasesinpatientswithceliacdisease