Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals
ABSTRACT Background: Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system that caused multiple epidemiological outbreaks in Peru during 2018 and 2019. It is usually diagnosed using the Brighton criteria (BC). Objective: We aimed to determine the performance of Pe...
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Thieme Revinter Publicações
2022-08-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022000600601&tlng=en |
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| author | Marco Malaga Aaron Rodriguez-Calienes Victor Velasquez-Rimachi Carlos Alva-Diaz |
| author_facet | Marco Malaga Aaron Rodriguez-Calienes Victor Velasquez-Rimachi Carlos Alva-Diaz |
| author_sort | Marco Malaga |
| collection | DOAJ |
| description | ABSTRACT Background: Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system that caused multiple epidemiological outbreaks in Peru during 2018 and 2019. It is usually diagnosed using the Brighton criteria (BC). Objective: We aimed to determine the performance of Peruvian neurologists in diagnosing GBS based on the BC, along with its associated factors. Methods: This was a retrospective multicenter cohort study. We included patients diagnosed with GBS between 2007 and 2018 in three public hospitals in Lima, Peru. We collected data regarding demographic, clinical and management characteristics. We evaluated the use of the BC for confirmatory diagnosis of GBS and developed a logistic regression model to identify factors associated with its use. Results: Out of 328 cases, we reviewed 201 available charts. The median age was 48 years, with male predominance. Over half of the patients presented an inadequate motor examination according to their Medical Research Council (MRC) score. Additional testing included lumbar puncture and electrophysiological testing, in over 70% of the cases. The BC showed certainty level 1 in 13.4% and levels 2 and 3 in 18.3%. Neither the quality of the motor examination nor the type of institution showed any association with the BC. Conclusions: Level 1 diagnostic certainty of the BC was met in less than one quarter of the cases with a GBS diagnosis in three centers in Lima, Peru, between 2007 and 2018. This level was not significantly associated with being treated in a specialized institute, rather than in a general hospital. |
| format | Article |
| id | doaj-art-5c0ab8211a43408b981fc0d9dbfe86e4 |
| institution | Kabale University |
| issn | 1678-4227 |
| language | English |
| publishDate | 2022-08-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-5c0ab8211a43408b981fc0d9dbfe86e42025-08-20T03:34:28ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272022-08-0180660160610.1590/0004-282x-anp-2021-0225Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitalsMarco Malagahttps://orcid.org/0000-0002-6477-8423Aaron Rodriguez-Calieneshttps://orcid.org/0000-0002-8413-6954Victor Velasquez-Rimachihttps://orcid.org/0000-0002-9350-7171Carlos Alva-Diazhttps://orcid.org/0000-0003-3584-7298ABSTRACT Background: Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system that caused multiple epidemiological outbreaks in Peru during 2018 and 2019. It is usually diagnosed using the Brighton criteria (BC). Objective: We aimed to determine the performance of Peruvian neurologists in diagnosing GBS based on the BC, along with its associated factors. Methods: This was a retrospective multicenter cohort study. We included patients diagnosed with GBS between 2007 and 2018 in three public hospitals in Lima, Peru. We collected data regarding demographic, clinical and management characteristics. We evaluated the use of the BC for confirmatory diagnosis of GBS and developed a logistic regression model to identify factors associated with its use. Results: Out of 328 cases, we reviewed 201 available charts. The median age was 48 years, with male predominance. Over half of the patients presented an inadequate motor examination according to their Medical Research Council (MRC) score. Additional testing included lumbar puncture and electrophysiological testing, in over 70% of the cases. The BC showed certainty level 1 in 13.4% and levels 2 and 3 in 18.3%. Neither the quality of the motor examination nor the type of institution showed any association with the BC. Conclusions: Level 1 diagnostic certainty of the BC was met in less than one quarter of the cases with a GBS diagnosis in three centers in Lima, Peru, between 2007 and 2018. This level was not significantly associated with being treated in a specialized institute, rather than in a general hospital.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022000600601&tlng=enGuillain-Barré SyndromeEvidence-Based PracticeEvidence-Based Medicine |
| spellingShingle | Marco Malaga Aaron Rodriguez-Calienes Victor Velasquez-Rimachi Carlos Alva-Diaz Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals Arquivos de Neuro-Psiquiatria Guillain-Barré Syndrome Evidence-Based Practice Evidence-Based Medicine |
| title | Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals |
| title_full | Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals |
| title_fullStr | Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals |
| title_full_unstemmed | Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals |
| title_short | Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals |
| title_sort | diagnosis of guillain barre syndrome and use of brighton criteria in peruvian hospitals |
| topic | Guillain-Barré Syndrome Evidence-Based Practice Evidence-Based Medicine |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022000600601&tlng=en |
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