Pharmacoinformation analysis of the molecules of the drug Klimaktoplan
An analysis of an array of publications on naturaL extracts of tsimitsifuga, sepia, sanguinaria included in the preparation KLimaktoplan, showed that only the extracts of tsimitsifugi have more than 800 studies. The main active principles of the Klimaktoplan are synergistically interacting triterpen...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
LLC “Publisher OKI”
2018-02-01
|
| Series: | Фармакокинетика и Фармакодинамика |
| Subjects: | |
| Online Access: | https://www.pharmacokinetica.ru/jour/article/view/51 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850062643692306432 |
|---|---|
| author | I. Yu. Torshin O. A. Gromova N. I. Tapilskaya |
| author_facet | I. Yu. Torshin O. A. Gromova N. I. Tapilskaya |
| author_sort | I. Yu. Torshin |
| collection | DOAJ |
| description | An analysis of an array of publications on naturaL extracts of tsimitsifuga, sepia, sanguinaria included in the preparation KLimaktoplan, showed that only the extracts of tsimitsifugi have more than 800 studies. The main active principles of the Klimaktoplan are synergistically interacting triterpene gLycosides, cymic acid derivatives of cymicifuge and naturaL pigments - brown melanin (sepia) and red sanguinarine (extract of Canadian sanguinaria). The results of fundamental and clinical studies of molecules of natural extracts in the KlimaktopLan indicate the following pharmacologicaL effects: anti-inflammatory, antidiabetic, vasodilator, hepatoprotective, spasmolytic, antiatherosclerotic, antitumor. Combination of components in the Klimaktoplan causes the effectiveness of the drug not onLy for the treatment of hot flashes, but a comorbid pathoLogy characteristic of the postmenopausal period. The possibility of combining extracts of Cimicifuga with other natural extracts (sepia, Canadian sanguinaria, etc.) is considered. |
| format | Article |
| id | doaj-art-5c05ddcba7cb469a8bd8cb0d714d5049 |
| institution | DOAJ |
| issn | 2587-7836 2686-8830 |
| language | Russian |
| publishDate | 2018-02-01 |
| publisher | LLC “Publisher OKI” |
| record_format | Article |
| series | Фармакокинетика и Фармакодинамика |
| spelling | doaj-art-5c05ddcba7cb469a8bd8cb0d714d50492025-08-20T02:49:52ZrusLLC “Publisher OKI”Фармакокинетика и Фармакодинамика2587-78362686-88302018-02-0101364610.24411/2587-7836-2018-10005.50Pharmacoinformation analysis of the molecules of the drug KlimaktoplanI. Yu. Torshin0O. A. Gromova1N. I. Tapilskaya2FederaL Research Center “Computer Science and Control“ of the Russian Academy of SciencesFederaL Research Center “Computer Science and Control“ of the Russian Academy of SciencesFederaL State Budgetary Scientific Institution “The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott”An analysis of an array of publications on naturaL extracts of tsimitsifuga, sepia, sanguinaria included in the preparation KLimaktoplan, showed that only the extracts of tsimitsifugi have more than 800 studies. The main active principles of the Klimaktoplan are synergistically interacting triterpene gLycosides, cymic acid derivatives of cymicifuge and naturaL pigments - brown melanin (sepia) and red sanguinarine (extract of Canadian sanguinaria). The results of fundamental and clinical studies of molecules of natural extracts in the KlimaktopLan indicate the following pharmacologicaL effects: anti-inflammatory, antidiabetic, vasodilator, hepatoprotective, spasmolytic, antiatherosclerotic, antitumor. Combination of components in the Klimaktoplan causes the effectiveness of the drug not onLy for the treatment of hot flashes, but a comorbid pathoLogy characteristic of the postmenopausal period. The possibility of combining extracts of Cimicifuga with other natural extracts (sepia, Canadian sanguinaria, etc.) is considered.https://www.pharmacokinetica.ru/jour/article/view/51менопаузацимицифугамеланинсепиясангвинаринклимактопланmenopausecimicifugamelaninsepiasanguineklimaktoplan |
| spellingShingle | I. Yu. Torshin O. A. Gromova N. I. Tapilskaya Pharmacoinformation analysis of the molecules of the drug Klimaktoplan Фармакокинетика и Фармакодинамика менопауза цимицифуга меланин сепия сангвинарин климактоплан menopause cimicifuga melanin sepia sanguine klimaktoplan |
| title | Pharmacoinformation analysis of the molecules of the drug Klimaktoplan |
| title_full | Pharmacoinformation analysis of the molecules of the drug Klimaktoplan |
| title_fullStr | Pharmacoinformation analysis of the molecules of the drug Klimaktoplan |
| title_full_unstemmed | Pharmacoinformation analysis of the molecules of the drug Klimaktoplan |
| title_short | Pharmacoinformation analysis of the molecules of the drug Klimaktoplan |
| title_sort | pharmacoinformation analysis of the molecules of the drug klimaktoplan |
| topic | менопауза цимицифуга меланин сепия сангвинарин климактоплан menopause cimicifuga melanin sepia sanguine klimaktoplan |
| url | https://www.pharmacokinetica.ru/jour/article/view/51 |
| work_keys_str_mv | AT iyutorshin pharmacoinformationanalysisofthemoleculesofthedrugklimaktoplan AT oagromova pharmacoinformationanalysisofthemoleculesofthedrugklimaktoplan AT nitapilskaya pharmacoinformationanalysisofthemoleculesofthedrugklimaktoplan |