Glycyrol targets Pneumolysin (PLY) oligomerization to reduce Streptococcus pneumoniae toxicity

Glycyrol targets Pneumolysin (PLY) oligomerization to reduce Streptococcus pneumoniae toxicity

Aim of the studyExploring the potential of glycyrol to reduce the invasiveness of Streptococcus pneumoniae (S. pneumoniae).Materials and MethodsCell experiments were performed using A549 alveolar epithelial cells and S. pneumoniae D39. Glycyrol was added to A549 cells mixed with or without Pneumolys...

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Bibliographic Details
Main Authors: Yudi Li, Hongji Wu, Yibo Hu, Haoji Meng, Yan Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
glycyrol
PLY
Streptococcus pneumoniae
TCM
toxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1478135/full
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