Comparison of Dentoalveolar Changes with Miniscrew-Assisted Versus Conventional Rapid Palatal Expansion in Growing Patients: A Systematic Review and Meta-Analysis
Background: This meta-analysis aimed to evaluate the dentoalveolar changes of miniscrew-assisted rapid palatal expansion (MARPE) compared with conventional rapid palatal expansion (CRPE) in growing patients (≤16 years). Methods: A systematic and comprehensive literature search was carried out indepe...
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2025-07-01
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| author | Hwang bin Lee Jong-Moon Chae Jae Hyun Park Na Jin Kim Sung-Hoon Han |
| author_facet | Hwang bin Lee Jong-Moon Chae Jae Hyun Park Na Jin Kim Sung-Hoon Han |
| author_sort | Hwang bin Lee |
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| description | Background: This meta-analysis aimed to evaluate the dentoalveolar changes of miniscrew-assisted rapid palatal expansion (MARPE) compared with conventional rapid palatal expansion (CRPE) in growing patients (≤16 years). Methods: A systematic and comprehensive literature search was carried out independently by two reviewers using both MeSH terms and free-text keywords across PubMed, the Cochrane Library, and Embase, with studies published through February 2025 included. The risk of bias was assessed using the Cochrane ROB 2.0 tool. The GRADE system was employed to determine evidence quality. Results: Of the 462 initially screened articles, 6 met the inclusion criteria and were selected for quantitative synthesis. Most studies had a low risk of bias with some concerns in reporting. The pooled standardized mean difference (SMD) for tooth inclination changes in CRPE compared with MARPE was 0.98 (95% confidence interval (CI), 0.54 to 1.42; <i>p</i> < 0.01). The test for overall effect was significant (<i>p</i> < 0.01), but no significant differences were found between the subgroups. The pooled SMD for buccal bone thickness changes in CRPE compared with MARPE was 0.69 (95% CI, 0.37 to 1.00; <i>p</i> < 0.01). The test for overall effect was significant (<i>p</i> < 0.01), and there were substantial differences between the subgroups. The supporting evidence ranged in certainty from moderate to low. Conclusions: MARPE was more effective than CRPE in minimizing the buccal tipping and buccal bone loss of the maxillary first premolars and first molars. However, to further confirm these outcomes and guide evidence-based clinical practice, well-designed randomized controlled trials with long-term follow-up are necessary. |
| format | Article |
| id | doaj-art-5bfe0a4b71cf48e6a577f2607aa08472 |
| institution | Kabale University |
| issn | 2076-3417 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj-art-5bfe0a4b71cf48e6a577f2607aa084722025-08-20T03:36:38ZengMDPI AGApplied Sciences2076-34172025-07-011515832610.3390/app15158326Comparison of Dentoalveolar Changes with Miniscrew-Assisted Versus Conventional Rapid Palatal Expansion in Growing Patients: A Systematic Review and Meta-AnalysisHwang bin Lee0Jong-Moon Chae1Jae Hyun Park2Na Jin Kim3Sung-Hoon Han4Orthodontics, Graduate School of Clinical Dental Science, The Catholic University of Korea, Seoul 06591, Republic of KoreaDepartment of Orthodontics, School of Dentistry, University of Wonkwang, Iksan 54538, Republic of KoreaPostgraduate Orthodontic Program, Arizona School of Dentistry & Oral Health, A.T. Still University, Mesa, AZ 85206, USAMedical Library, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaDepartment of Orthodontics, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaBackground: This meta-analysis aimed to evaluate the dentoalveolar changes of miniscrew-assisted rapid palatal expansion (MARPE) compared with conventional rapid palatal expansion (CRPE) in growing patients (≤16 years). Methods: A systematic and comprehensive literature search was carried out independently by two reviewers using both MeSH terms and free-text keywords across PubMed, the Cochrane Library, and Embase, with studies published through February 2025 included. The risk of bias was assessed using the Cochrane ROB 2.0 tool. The GRADE system was employed to determine evidence quality. Results: Of the 462 initially screened articles, 6 met the inclusion criteria and were selected for quantitative synthesis. Most studies had a low risk of bias with some concerns in reporting. The pooled standardized mean difference (SMD) for tooth inclination changes in CRPE compared with MARPE was 0.98 (95% confidence interval (CI), 0.54 to 1.42; <i>p</i> < 0.01). The test for overall effect was significant (<i>p</i> < 0.01), but no significant differences were found between the subgroups. The pooled SMD for buccal bone thickness changes in CRPE compared with MARPE was 0.69 (95% CI, 0.37 to 1.00; <i>p</i> < 0.01). The test for overall effect was significant (<i>p</i> < 0.01), and there were substantial differences between the subgroups. The supporting evidence ranged in certainty from moderate to low. Conclusions: MARPE was more effective than CRPE in minimizing the buccal tipping and buccal bone loss of the maxillary first premolars and first molars. However, to further confirm these outcomes and guide evidence-based clinical practice, well-designed randomized controlled trials with long-term follow-up are necessary.https://www.mdpi.com/2076-3417/15/15/8326palatal expansion techniqueorthodontic anchorage proceduresbone resorptioncone-beam computed tomographygrowing patientsMARPE |
| spellingShingle | Hwang bin Lee Jong-Moon Chae Jae Hyun Park Na Jin Kim Sung-Hoon Han Comparison of Dentoalveolar Changes with Miniscrew-Assisted Versus Conventional Rapid Palatal Expansion in Growing Patients: A Systematic Review and Meta-Analysis Applied Sciences palatal expansion technique orthodontic anchorage procedures bone resorption cone-beam computed tomography growing patients MARPE |
| title | Comparison of Dentoalveolar Changes with Miniscrew-Assisted Versus Conventional Rapid Palatal Expansion in Growing Patients: A Systematic Review and Meta-Analysis |
| title_full | Comparison of Dentoalveolar Changes with Miniscrew-Assisted Versus Conventional Rapid Palatal Expansion in Growing Patients: A Systematic Review and Meta-Analysis |
| title_fullStr | Comparison of Dentoalveolar Changes with Miniscrew-Assisted Versus Conventional Rapid Palatal Expansion in Growing Patients: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Comparison of Dentoalveolar Changes with Miniscrew-Assisted Versus Conventional Rapid Palatal Expansion in Growing Patients: A Systematic Review and Meta-Analysis |
| title_short | Comparison of Dentoalveolar Changes with Miniscrew-Assisted Versus Conventional Rapid Palatal Expansion in Growing Patients: A Systematic Review and Meta-Analysis |
| title_sort | comparison of dentoalveolar changes with miniscrew assisted versus conventional rapid palatal expansion in growing patients a systematic review and meta analysis |
| topic | palatal expansion technique orthodontic anchorage procedures bone resorption cone-beam computed tomography growing patients MARPE |
| url | https://www.mdpi.com/2076-3417/15/15/8326 |
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