Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer Model

Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer Model

Saved in:

Bibliographic Details
Main Authors:	Jaqueline A. Duarte, Eliza R. Gomes, Geovanni D. Cassali, Pierre Sicard, Sylvain Richard, Philippe Legrand, Andre L.B. de Barros, Elaine A. Leite
Format:	Article
Language:	English
Published:	American Chemical Society 2025-07-01
Series:	ACS Omega
Online Access:	https://doi.org/10.1021/acsomega.5c04484
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Silicone Doped Chitosan-Acrylamide Coencapsulated Urea Fertilizer: An Approach to Controlled Release Fertilizers
by: Sempeho Ibahati Siafu
Published: (2017-01-01)

Reducing toxicity and enhancing efficacy of doxorubicin by liposomal doxorubicin and aprepitant in breast cancer
by: Atefeh Ghahremanloo, et al.
Published: (2025-03-01)

Place of pegylated liposomal doxorubicin in the therapy of metastatic breast cancer
by: E. V. Artamonova
Published: (2016-09-01)

The use of pegylated liposomal doxorubicin in metastatic soft tissue sarcoma
by: Trang Pham, et al.
Published: (2025-04-01)

Diffuse Erythematous Follicular Eruption Induced by Pegylated Liposomal Doxorubicin
by: Zhong L, et al.
Published: (2025-04-01)

Substituting Doxorubicin with Nonpegylated Liposomal Doxorubicin for the Treatment of Early Breast Cancer: Results of a Retrospective Study
by: Neville Davidson, et al.
Published: (2014-01-01)

Pegylated liposomal doxorubicin (Caelyx): contemporary aspects of its application in hematology
by: O. A. Rukavitsin, et al.
Published: (2022-11-01)

The supramolecular processing of liposomal doxorubicin hinders its therapeutic efficacy in cells
by: Annalisa Carretta, et al.
Published: (2024-09-01)

The impact of size for liposomes modified with pH-responsive β-glucan derivatives on the initiation of cellular and humoral immune responses in murine models
by: Shin Yanagihara, et al.
Published: (2024-12-01)

Sodium oleate functionalized simvastatin liposomes: boosting endosomal escape and anticancer efficacy in triple negative breast cancer
by: Ebrahim Sadaqa, et al.
Published: (2025-03-01)

Pulmonary Fibrosis after Pegylated Liposomal Doxorubicin in Elderly Patient with Cutaneous Angiosarcoma
by: Marco Mazzotta, et al.
Published: (2016-01-01)

The effectiveness of liposomal doxorubicin hydrochloride in combination with cyclophosphan in the treatment of breast cancer in an experiment
by: L. A. Balykova, et al.
Published: (2021-12-01)

Preparation and Characterization of Hydrophobin 4-Coated Liposomes for Doxorubicin Delivery to Cancer Cells
by: Fatma Hande Osmanagaoglu, et al.
Published: (2024-10-01)

Enhancing targeted delivery and efficacy of PEGylated liposomal doxorubicin with liposomal minoxidil: comprehensive in silico, in vitro, and in vivo tumor model studies
by: Vahideh Mohammadzadeh, et al.
Published: (2025-12-01)

Simvastatin-loaded liposomal nanoparticles as treatment for adenomyosis in a patient-derived xenograft mouse model: a pilot study
by: Rachel Michel, et al.
Published: (2025-12-01)

Antitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer.
by: Mahavir B Chougule, et al.
Published: (2011-03-01)

Pegylated liposomal doxorubicin does not affect cardiac function in patients treated for gynecologic malignancies
by: Khrystyna Levytska, et al.
Published: (2025-04-01)

Characterization and in vitro anticancer study of PEGylated liposome dually loaded with ferulic acid and doxorubicin
by: Andang Miatmoko, et al.
Published: (2025-01-01)

Synergistic effect of antitumor activity of doxorubicin and bicomponent nanostructures based on aluminum oxide
by: O. V. Bakina, et al.
Published: (2020-04-01)

Enhanced in vivo Stability and Antitumor Efficacy of PEGylated Liposomes of Paclitaxel Palmitate Prodrug
by: Wu X, et al.
Published: (2024-11-01)

In Vitro Study of Antitumor and Antimicrobial Activity of a Preparation of Pegylated Liposomes with Sanguinarine
by: S. V. Lutsenko, et al.
Published: (2020-05-01)

An Effective Liposome-Based Nanodelivery System for Naphthalene Derivative Polyamines with Antitumor Activity
by: Isabel Pont, et al.
Published: (2024-10-01)

An pH-responsive liposome for the targeted treatment of Helicobacter pylori
by: Huihua Dong, et al.
Published: (2025-10-01)

Phase I Trial of Pegylated Liposomal Doxorubicin Combined with Ifosfamide for Advanced Soft Tissue Sarcoma
by: Ye T, et al.
Published: (2025-08-01)

Acute Kidney Injury Secondary to Pegylated Liposomal Doxorubicin-Associated Renal-limited Thrombotic Microangiopathy
by: Tarek S. Karam, et al.
Published: (2025-05-01)

Evaluation of the antitumor effects of Echovirus in combination with Doxorubicin in a mouse model of breast cancer
by: Fatemeh Aminian, et al.
Published: (2025-06-01)

Potentiating Effect of Nitric Oxide Donor on Antitumor Activity of Doxorubicin in Glioblastoma-Bearing Rats
by: A. I. Alekseeva, et al.
Published: (2020-05-01)

Synergistic Antitumor Effect of Doxorubicin and Tacrolimus (FK506) on Hepatocellular Carcinoma Cell Lines
by: Francesca Capone, et al.
Published: (2014-01-01)

Engineered celastrol liposomes with glycyrrhizic acid augment synergistic antitumor efficacy in breast cancer
by: Wei Zhang, et al.
Published: (2025-05-01)

Reversible Electroporation–Mediated Liposomal Doxorubicin Delivery to Tumors Can Be Monitored With Zr-Labeled Reporter Nanoparticles
by: Govindarajan Srimathveeravalli PhD, et al.
Published: (2018-02-01)

Early transcriptional alteration of histone deacetylases in a murine model of doxorubicin-induced cardiomyopathy.
by: Izabela Piotrowska, et al.
Published: (2017-01-01)

Doxorubicin enhanced the antitumor efficacy of sonodynamic therapy with photosensitizer photolon in an <i>in vivo</i> experiment
by: D. A. Tzerkovsky, et al.
Published: (2024-12-01)

Improved Antitumor Efficiency of N4-Tetradecyloxycarbonyl Gemcitabine-Loaded Liposomes for Pancreatic Cancer Chemotherapy
by: Wang D, et al.
Published: (2024-12-01)

Statement of Retraction: Bicomponent polymeric micelles for pH-controlled delivery of doxorubicin
Published: (2024-12-01)

Long-term effect of pegylated liposomal doxorubicin in recurrent platinum-resistant ovarian cancer: а clinical case
by: I. A. Pokataev, et al.
Published: (2015-11-01)

Cardiotoxicity of combined pegylated liposomal doxorubicin and bevacizumab therapy: a propensity-matched cohort study and disproportionality analysis
by: Christopher W. Hoeger, et al.
Published: (2025-07-01)

Co-delivery of doxorubicin and SATB1 shRNA by thermosensitive magnetic cationic liposomes for gastric cancer therapy.
by: Zhao Peng, et al.
Published: (2014-01-01)

Remote Co-Loading of Doxorubicin and Hydralazine into PEGylated Liposomes: In Vitro Anti-Proliferative Effect Against Breast Cancer
by: Walhan Alshaer, et al.
Published: (2025-03-01)

Thirty years from FDA approval of pegylated liposomal doxorubicin (Doxil/Caelyx): an updated analysis and future perspective
by: Alberto A Gabizon, et al.
Published: (2025-01-01)

Complete remission in a rare pelvic angiosarcoma with liposomal doxorubicin: A comprehensive case report and review of literature
by: Truls Gråberg, et al.
Published: (2025-02-01)