Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer Model

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Main Authors: Jaqueline A. Duarte, Eliza R. Gomes, Geovanni D. Cassali, Pierre Sicard, Sylvain Richard, Philippe Legrand, Andre L.B. de Barros, Elaine A. Leite
Format: Article
Language:English
Published: American Chemical Society 2025-07-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.5c04484
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author Jaqueline A. Duarte
Eliza R. Gomes
Geovanni D. Cassali
Pierre Sicard
Sylvain Richard
Philippe Legrand
Andre L.B. de Barros
Elaine A. Leite
author_facet Jaqueline A. Duarte
Eliza R. Gomes
Geovanni D. Cassali
Pierre Sicard
Sylvain Richard
Philippe Legrand
Andre L.B. de Barros
Elaine A. Leite
author_sort Jaqueline A. Duarte
collection DOAJ
format Article
id doaj-art-5bfd67f2435d4dca9884e0c6e47cecb8
institution Kabale University
issn 2470-1343
language English
publishDate 2025-07-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-5bfd67f2435d4dca9884e0c6e47cecb82025-08-20T03:29:58ZengAmerican Chemical SocietyACS Omega2470-13432025-07-011028310463105810.1021/acsomega.5c04484Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer ModelJaqueline A. Duarte0Eliza R. Gomes1Geovanni D. Cassali2Pierre Sicard3Sylvain Richard4Philippe Legrand5Andre L.B. de Barros6Elaine A. Leite7Department of Pharmaceutical Products, Faculty of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, BrazilDepartment of Pharmaceutical Products, Faculty of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, BrazilDepartment of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, BrazilPhyMedExp, IPAM/Biocampus, INSERM/CNRS/Université de Montpellier, Montpellier, FrancePhyMedExp, IPAM/Biocampus, INSERM/CNRS/Université de Montpellier, Montpellier, FranceInstitut Charles Gerhardt Montpellier (ICGM), Université de Montpellier, CNRS, ENSCM, Montpellier, FranceDepartment of Clinical and Toxicological Analyses, Faculty of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, BrazilDepartment of Pharmaceutical Products, Faculty of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazilhttps://doi.org/10.1021/acsomega.5c04484
spellingShingle Jaqueline A. Duarte
Eliza R. Gomes
Geovanni D. Cassali
Pierre Sicard
Sylvain Richard
Philippe Legrand
Andre L.B. de Barros
Elaine A. Leite
Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer Model
ACS Omega
title Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer Model
title_full Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer Model
title_fullStr Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer Model
title_full_unstemmed Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer Model
title_short Evaluation of the Antitumor Effectiveness and Toxicity of pH-Sensitive Liposomes Coencapsulating Doxorubicin and Simvastatin in a Murine Breast Cancer Model
title_sort evaluation of the antitumor effectiveness and toxicity of ph sensitive liposomes coencapsulating doxorubicin and simvastatin in a murine breast cancer model
url https://doi.org/10.1021/acsomega.5c04484
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