Low intensity trans-spinal focused ultrasound reduces mechanical sensitivity and suppresses spinal microglia activation in rats with chronic constriction injury

Low intensity trans-spinal focused ultrasound reduces mechanical sensitivity and suppresses spinal microglia activation in rats with chronic constriction injury

Abstract Low intensity, trans-spinal focused ultrasound (tsFUS) is a noninvasive neuromodulation approach that has been shown to modulate spinal circuit excitability in healthy rats. Here, we evaluated the potential of tsFUS for alleviating neuropathic pain by testing it in a chronic constriction in...

Full description

Saved in:
Bibliographic Details
Main Authors: Weiguo Song, Alice Giannotti, Alexandra Bekiaridou, Ona Bloom, Stavros Zanos
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Bioelectronic Medicine
Subjects:
Trans-spinal focused ultrasound stimulation
Noninvasive neuromodulation
Von Frey threshold
Pain
Flow cytometry
Microglia
Online Access:https://doi.org/10.1186/s42234-025-00170-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items