Towards increased strength and retained ductility of Zn–Mg-(Ag) materials for medical devices by adopting powder metallurgy processing routes
The development of bioabsorbable zinc-based alloys with tailored mechanical properties and biocompatibility holds great promise for advancing medical implant technology. In this study, Zn–Mg and Zn–Mg–Ag alloys were synthesized using mechanical alloying (MA) followed by extrusion to achieve a combin...
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Elsevier
2025-07-01
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| Series: | Journal of Materials Research and Technology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785425016072 |
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| author | Jiří Kubásek Selase Torkornoo David Nečas Ingrid McCarroll Vojtěch Hybášek Baptiste Gault Eva Jablonská Črtomir Donik Irena Paulin Peter Gogola Martin Kusý Zdeněk Míchal Jaroslav Fojt Miroslav Čavojský Jan Duchoň Markéta Jarošová Jaroslav Čapek |
| author_facet | Jiří Kubásek Selase Torkornoo David Nečas Ingrid McCarroll Vojtěch Hybášek Baptiste Gault Eva Jablonská Črtomir Donik Irena Paulin Peter Gogola Martin Kusý Zdeněk Míchal Jaroslav Fojt Miroslav Čavojský Jan Duchoň Markéta Jarošová Jaroslav Čapek |
| author_sort | Jiří Kubásek |
| collection | DOAJ |
| description | The development of bioabsorbable zinc-based alloys with tailored mechanical properties and biocompatibility holds great promise for advancing medical implant technology. In this study, Zn–Mg and Zn–Mg–Ag alloys were synthesized using mechanical alloying (MA) followed by extrusion to achieve a combination of enhanced strength, ductility, and corrosion resistance. MA for 4 h produced ultrafine-grained powders incorporating Mg2Zn11 intermetallic phases and oxide particles, which contributed to microstructure stabilization during subsequent processing. Extrusion consolidated these powders into dense materials with a uniform grain size of ∼700 nm, exhibiting ultimate tensile strengths up to 435 MPa and elongation to fracture of ∼12 %, representing a significant improvement over conventional processing methods. The addition of silver further enhanced the antibacterial properties, demonstrating notable efficacy against Staphylococcus epidermidis, while maintaining non-cytotoxic behavior in vitro. Corrosion rates remained low, with uniform surface degradation and the formation of protective corrosion layers. This work highlights the efficacy of combining powder metallurgy techniques to bioabsorbable zinc-based alloys with exceptional mechanical performance, corrosion behavior and in vitro cytocompatibility, providing a pathway for next-generation biodegradable medical devices. |
| format | Article |
| id | doaj-art-5bf38c3731b146509f1b1a2fc8495c19 |
| institution | Kabale University |
| issn | 2238-7854 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Materials Research and Technology |
| spelling | doaj-art-5bf38c3731b146509f1b1a2fc8495c192025-08-20T03:50:53ZengElsevierJournal of Materials Research and Technology2238-78542025-07-01374345436110.1016/j.jmrt.2025.06.185Towards increased strength and retained ductility of Zn–Mg-(Ag) materials for medical devices by adopting powder metallurgy processing routesJiří Kubásek0Selase Torkornoo1David Nečas2Ingrid McCarroll3Vojtěch Hybášek4Baptiste Gault5Eva Jablonská6Črtomir Donik7Irena Paulin8Peter Gogola9Martin Kusý10Zdeněk Míchal11Jaroslav Fojt12Miroslav Čavojský13Jan Duchoň14Markéta Jarošová15Jaroslav Čapek16University of Chemistry and Technology Prague, Faculty of Chemical Technology, Department of Metals and Corrosion Engineering, Technická 5, 6 – Dejvice, 166 28, Praha, Czech Republic; Corresponding author.Department of Microstructure Physics and Alloy Design, Max-Planck-Institut für Nachhaltige Materialien GmbH, Max-Planck-Straße 1, 40237, Düsseldorf, Germany; Corresponding author.University of Chemistry and Technology Prague, Faculty of Chemical Technology, Department of Metals and Corrosion Engineering, Technická 5, 6 – Dejvice, 166 28, Praha, Czech RepublicDepartment of Microstructure Physics and Alloy Design, Max-Planck-Institut für Nachhaltige Materialien GmbH, Max-Planck-Straße 1, 40237, Düsseldorf, GermanyUniversity of Chemistry and Technology Prague, Faculty of Chemical Technology, Department of Metals and Corrosion Engineering, Technická 5, 6 – Dejvice, 166 28, Praha, Czech RepublicDepartment of Microstructure Physics and Alloy Design, Max-Planck-Institut für Nachhaltige Materialien GmbH, Max-Planck-Straße 1, 40237, Düsseldorf, Germany; Department of Materials, Imperial College London, Royal School of Mines, Exhibition Road, London, SW7 2AZ, UKUniversity of Chemistry and Technology Prague, Department of Biochemistry and Microbiology, Technická 5, 6 – Dejvice, 166 28, Praha, Czech RepublicInstitute of Metals and Technology, Lepi pot 11, SI-1000, Ljubljana, SloveniaInstitute of Metals and Technology, Lepi pot 11, SI-1000, Ljubljana, SloveniaSlovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava, Ulica Jána Bottu 2781/25, 91724, Trnava, the Slovak RepublicSlovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava, Ulica Jána Bottu 2781/25, 91724, Trnava, the Slovak RepublicUniversity of Chemistry and Technology Prague, Department of Biochemistry and Microbiology, Technická 5, 6 – Dejvice, 166 28, Praha, Czech RepublicUniversity of Chemistry and Technology Prague, Faculty of Chemical Technology, Department of Metals and Corrosion Engineering, Technická 5, 6 – Dejvice, 166 28, Praha, Czech RepublicInstitute of Materials and Machine Mechanics, Slovak Academy of Sciences, Dúbravská cesta 9/6319, 845 13, Bratislava, the Slovak RepublicFZU – Institute of Physics of the Czech Academy of Sciences, Na Slovance 1999/2, 8, Prague, 18200, Czech RepublicFZU – Institute of Physics of the Czech Academy of Sciences, Cukrovarnická 112/10, 6, Prague, 16200, Czech RepublicUniversity of Chemistry and Technology Prague, Faculty of Chemical Technology, Department of Metals and Corrosion Engineering, Technická 5, 6 – Dejvice, 166 28, Praha, Czech Republic; FZU – Institute of Physics of the Czech Academy of Sciences, Na Slovance 1999/2, 8, Prague, 18200, Czech RepublicThe development of bioabsorbable zinc-based alloys with tailored mechanical properties and biocompatibility holds great promise for advancing medical implant technology. In this study, Zn–Mg and Zn–Mg–Ag alloys were synthesized using mechanical alloying (MA) followed by extrusion to achieve a combination of enhanced strength, ductility, and corrosion resistance. MA for 4 h produced ultrafine-grained powders incorporating Mg2Zn11 intermetallic phases and oxide particles, which contributed to microstructure stabilization during subsequent processing. Extrusion consolidated these powders into dense materials with a uniform grain size of ∼700 nm, exhibiting ultimate tensile strengths up to 435 MPa and elongation to fracture of ∼12 %, representing a significant improvement over conventional processing methods. The addition of silver further enhanced the antibacterial properties, demonstrating notable efficacy against Staphylococcus epidermidis, while maintaining non-cytotoxic behavior in vitro. Corrosion rates remained low, with uniform surface degradation and the formation of protective corrosion layers. This work highlights the efficacy of combining powder metallurgy techniques to bioabsorbable zinc-based alloys with exceptional mechanical performance, corrosion behavior and in vitro cytocompatibility, providing a pathway for next-generation biodegradable medical devices.http://www.sciencedirect.com/science/article/pii/S2238785425016072ZincBioabsorbable materialsMechanical alloyingSpark plasma sinteringMicrostructure |
| spellingShingle | Jiří Kubásek Selase Torkornoo David Nečas Ingrid McCarroll Vojtěch Hybášek Baptiste Gault Eva Jablonská Črtomir Donik Irena Paulin Peter Gogola Martin Kusý Zdeněk Míchal Jaroslav Fojt Miroslav Čavojský Jan Duchoň Markéta Jarošová Jaroslav Čapek Towards increased strength and retained ductility of Zn–Mg-(Ag) materials for medical devices by adopting powder metallurgy processing routes Journal of Materials Research and Technology Zinc Bioabsorbable materials Mechanical alloying Spark plasma sintering Microstructure |
| title | Towards increased strength and retained ductility of Zn–Mg-(Ag) materials for medical devices by adopting powder metallurgy processing routes |
| title_full | Towards increased strength and retained ductility of Zn–Mg-(Ag) materials for medical devices by adopting powder metallurgy processing routes |
| title_fullStr | Towards increased strength and retained ductility of Zn–Mg-(Ag) materials for medical devices by adopting powder metallurgy processing routes |
| title_full_unstemmed | Towards increased strength and retained ductility of Zn–Mg-(Ag) materials for medical devices by adopting powder metallurgy processing routes |
| title_short | Towards increased strength and retained ductility of Zn–Mg-(Ag) materials for medical devices by adopting powder metallurgy processing routes |
| title_sort | towards increased strength and retained ductility of zn mg ag materials for medical devices by adopting powder metallurgy processing routes |
| topic | Zinc Bioabsorbable materials Mechanical alloying Spark plasma sintering Microstructure |
| url | http://www.sciencedirect.com/science/article/pii/S2238785425016072 |
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